Fig. 2
Evaluation of T7-EA activity by RNA-sequencing in Raw264.7 cells. a DEGs between T7-EA and T7 treatments. 1 × 106 Raw 264.7 cells were treated with 10 μM T7 or T7-EA for 24 h. Then, total RNA was extracted and purified for RNA-seq, and the DEGs among Mock, T7 and T7-EA groups were counted. b Gene expression patterns based on genes involved in the TLR signaling pathway after T7-EA or T7 treatment. All the genes in the TLR signaling were extracted from PathCards (https://pathcards.genecards.org), and the gene expression was analyzed in Mock, T7 and T7-EA treatment groups. DEGs, differentially expressed genes; T7, SZU-101