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Table 4 Correlation between PPARγ, Cox-1 and Cox-2 expression and clinicopathological or aggressiveness related parameters

From: Cytoplasmic PPARγ is a marker of poor prognosis in patients with Cox-1 negative primary breast cancers

 

PPARγ n = 143 to 262

Cox-1

Cox-2

Total

Nuclear

Cytoplasmic

n = 159 to 297

n = 153 to 285

Age

0.004

− 0.050

0.002

0.041

− 0.015

pT

0.118

− 0.037

0.113

− 0.049

− 0.066

pN

0.069

0.023

0.065

− 0.125*

− 0.043

Grade

0.007

− 0.205*

0.054

− 0.007

− 0.062

ER

− 0.119

0.117

− 0.142*

0.009

0.039

PR

− 0.048

0.038

− 0.049

− 0.018

0.012

HER2

0.157**

− 0.127*

0.173**

0.137*

0.090

Triple negative

0.076

− 0.062

0.085

− 0.043

− 0.052

Ki-67

0.116

− 0.039

0.119

0.084

0.155*

Focality

0.043

0.074

0.016

− 0.048

− 0.028

CD133

0.221**

− 0.007

0.230**

0.132*

0.378**

NCAD

0.412**

− 0.196**

0.447**

0.241**

0.461**

  1. Correlations are statistically significant for p < 0.05 (*) or p < 0.01 (**), using Spearman-Rho-Test