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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Oral typhoid vaccine Ty21a elicits antigen-specific resident memory CD4+ T cells in the human terminal ileum lamina propria and epithelial compartments

Fig. 3

S. Typhi-specific responses of terminal ileum LPMC CD4+CD103+ and CD8+CD103− TRM subsets in healthy individuals following oral Ty21a-immunization. The net percentages of S. Typhi-specific responses (IFNγ, IL-17A, IL-2, and TNFα) elicited by S. Typhi-infected autologous targets in a CD4+CD103+ and b CD4+CD103− TRM subsets were compared between Ty21a-vaccinated (n = 18; red symbols) and unvaccinated volunteers (n = 18; black symbols) with significant differences (*p < 0.05; **p < 0.005) indicated. Horizontal bars (black and red) represent median values

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