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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Identification of key genes controlling breast cancer stem cell characteristics via stemness indices analysis

Fig. 2

Identification of DEGs and stemness-related key modules in BRCA. a Differentially expressed genes: red indicates upregulated genes; green indicates downregulated genes and black indicates genes excluded by DEG screening criteria. b, c Identification of a co-expression module in BRCA. Each piece of the leaves on the cluster dendrogram corresponded to a gene, and those genes with similar expression patterns compose a branch (c). Correlation between gene modules and mRNAsi scores or EREG-mRNAsi. The upper row in each cell indicates the correlation coefficient ranging from − 1 to 1 of the correlation between a certain gene module and mRNAsi or EREG-mRNAsi. The lower row in each cell indicates the p-value (b). d, e The scatter plot of the top three important gene modules: turquoise module (d), green module (e) and brown module (f). Each circle indicates a gene, and those circles located in the upper right indicate the key genes in these modules

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