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Table 2 Characteristics of the TMA cohort (n = 140)

From: YAP1 is an independent prognostic marker in pancreatic cancer and associated with extracellular matrix remodeling

Variable

N

All patients

(n = 140)

Low YAP1 protein expression

(n = 70)

High YAP1 protein expression

(n = 70)

p

Age > 65 years

140

93 (66.4)

48 (68.6)

45 (64.3)

0.721

Female gender

140

66 (47.1)

35 (50)

31 (44.3)

0.612

BMI > 25 kg/m2

132

57 (43.2)

32 (47.1)

25 (39.1)

0.383

Smoking history

139

67 (48.2)

28 (40.6)

39 (55.7)

0.09

Diabetes mellitus

139

33 (23.7)

19 (27.1)

14 (20.3)

0.426

Symptoms at diagnosis

136

131 (96.3)

68 (100)

63 (92.6)

0.058

Tumor location (head)

140

117 (83.6)

62 (88.6)

55 (78.6)

0.17

Tumor size > 2 cm

139

117 (84.2)

60 (87)

57 (81.4)

0.487

T-stage ≥ T2

139

121 (87.1)

60 (87)

61 (87.1)

1

N-stage ≥ N1

138

104 (75.4)

53 (76.8)

51 (73.9)

0.844

AJCC-stage ≥ II

138

112 (81.2)

56 (81.2)

56 (81.2)

1

Histological grade ≥ 3

138

83 (60.1)

38 (55.9)

45 (64.3)

0.385

Positive resection margin

139

55 (39.6)

28 (40.6)

27 (38.6)

0.863

Adjuvant chemotherapy

135

113 (83.7)

60 (87)

53 (80.3)

0.355

Recurrence of disease

127

103 (81.1)

51 (79.7)

52 (82.5)

0.821

  1. N, number of non-missing values. Qualitative data are expressed as n (%)
  2. AJCC American Joint Committee on Cancer, BMI body mass index, N-stage nodal stage, T-stage tumor stage