Variable | N | All patients (n = 140) | Low YAP1 protein expression (n = 70) | High YAP1 protein expression (n = 70) | p |
---|---|---|---|---|---|
Age > 65 years | 140 | 93 (66.4) | 48 (68.6) | 45 (64.3) | 0.721 |
Female gender | 140 | 66 (47.1) | 35 (50) | 31 (44.3) | 0.612 |
BMI > 25 kg/m2 | 132 | 57 (43.2) | 32 (47.1) | 25 (39.1) | 0.383 |
Smoking history | 139 | 67 (48.2) | 28 (40.6) | 39 (55.7) | 0.09 |
Diabetes mellitus | 139 | 33 (23.7) | 19 (27.1) | 14 (20.3) | 0.426 |
Symptoms at diagnosis | 136 | 131 (96.3) | 68 (100) | 63 (92.6) | 0.058 |
Tumor location (head) | 140 | 117 (83.6) | 62 (88.6) | 55 (78.6) | 0.17 |
Tumor size > 2 cm | 139 | 117 (84.2) | 60 (87) | 57 (81.4) | 0.487 |
T-stage ≥ T2 | 139 | 121 (87.1) | 60 (87) | 61 (87.1) | 1 |
N-stage ≥ N1 | 138 | 104 (75.4) | 53 (76.8) | 51 (73.9) | 0.844 |
AJCC-stage ≥ II | 138 | 112 (81.2) | 56 (81.2) | 56 (81.2) | 1 |
Histological grade ≥ 3 | 138 | 83 (60.1) | 38 (55.9) | 45 (64.3) | 0.385 |
Positive resection margin | 139 | 55 (39.6) | 28 (40.6) | 27 (38.6) | 0.863 |
Adjuvant chemotherapy | 135 | 113 (83.7) | 60 (87) | 53 (80.3) | 0.355 |
Recurrence of disease | 127 | 103 (81.1) | 51 (79.7) | 52 (82.5) | 0.821 |