TY - JOUR AU - Wang, Daojuan AU - Wang, Tingyu AU - Wang, Rong AU - Zhang, Xinlin AU - Wang, Lei AU - Xiang, Zou AU - Zhuang, Lingjia AU - Shen, Shanmei AU - Wang, Hongwei AU - Gao, Qian AU - Wang, Yong PY - 2020 DA - 2020/02/17 TI - Suppression of p66Shc prevents hyperandrogenism-induced ovarian oxidative stress and fibrosis JO - Journal of Translational Medicine SP - 84 VL - 18 IS - 1 AB - Rats with hyperandrogen-induced polycystic ovary syndrome (PCOS) have been shown to develop ovarian oxidative stress (OS) and fibrosis. The Sirt1 agonist, resveratrol, can reduce OS through inhibiting p66Shc in other models of OS. SN - 1479-5876 UR - https://doi.org/10.1186/s12967-020-02249-4 DO - 10.1186/s12967-020-02249-4 ID - Wang2020 ER -