Table 1 Exhaustive radio-morphologic and molecular data on the evaluated NS nodules approached through CNB bioptic procedures
ID# | Gender | Age at diagnosis (yrs) | Lobe | Segment | Site | Diameter (mm) | Density M/NS | Histology | Architectural pattern | EGFR | ROS1 | EML4/ALK | PDL-1 (%) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | F | 78 | IRL | Posterior | P | 61 | M | Atypia/ADC | Atipic hyperplasia/ADC | wt | wt | wt | 5 |
2 | F | 53 | ILL | Lateral | P | 26 | NS | ADC | In situ, not mucinous | p.L861Q | wt | wt | 3 |
3 | F | 72 | SLL | Apico-posterior | P | 33 | M | ADC | Mucinous | wt | wt | wt | < 1 |
4 | M | 79 | SRL | Posterior | P | 30 | M | ADC | In situ | wt | wt | wt | < 1 |
5 | F | 62 | SRL | Apical | P | 26 | M | ADC | Papillary (10%) lepidic (20%) acinar (70%) | p. L858R | wt | wt | < 1 |
6 | F | 75 | SLL | Apico-posterior | M | 36 | M | ADC | Lepidic/60%) | wt | wt | wt | < 1 |
7 | F | 80 | SRL | Posterior | P | 28 | M | ADC | Acinar (60%) micropapillary (20%) solid (10%) lepidic (10%) | wt | wt | wt | < 1 |
8 | F | 46 | SRL | Apical | M | 15 | NS | ADC | Lepidic (60%) acinar (40%) | wt | wt | wt | < 1 |
9 | F | 59 | SRL | Apical | P | 16 | NS | ADC | Papillary (70%) Solid (30%) | p.G719A | wt | wt | 5 |
10 | M | 69 | SRL | Apical | P | 30 | NS | ADC | Well differentiated ADC | wt | wt | wt | 20 |
11 | F | 69 | SRL | Posterior | P | 20 | NS | ADC | Well differentiated ADC | wt | wt | wt | < 1 |
12 | M | 71 | SRL | Apical | P | 27 | M | ADC | Partially differentiated ADC | wt | wt | wt | < 1 |
13 | M | 71 | SRL | Anterior | M | 25 | M | ADC | Well differentiated ADC | wt | wt | wt | < 1 |
14 | M | 76 | SLL | Apico-posterior | M | 14 | M | ADC | Acinar (90%) Lepidic (10%) | wt | wt | wt | < 1 |
15 | M | 58 | IRL | Posterior | P | 43 | M | ADC | Acinar (60) Papillary (30%) Micropapillary (10%) | wt | wt | wt | < 1 |
16 | F | 81 | SRL | Anterior | P | 26 | M | ADC | Well differentiated ADC | wt | wt | wt | 52 |
17 | M | 71 | SRL | Anterior | M | 28 | M | ADC | Well differentiated ADC | wt | wt | wt | < 1 |
18 | M | 77 | SRL | Posterior | P | 22 | NS | ADC | Acinar (80%) Lepidic (20%) | wt | wt | wt | 11 |
19 | F | 62 | SRL | Posterior | M | 16 | NS | ADC | Partially differentiated ADC | wt | wt | wt | < 1 |
20 | F | 60 | SLL | Superior lingular | M | 30 | NS | ADC | Lepidic (60%) acinar(40%) | wt | wt | wt | < 1 |
21 | M | 75 | SRL | Posterior | P | 35 | NS | ADC | In situ, mucinous | wt | wt | wt | < 1 |
22 | F | 75 | SRL | Apical | P | 25 | M | ADC | Partially differentiated ADC, anthracosis | wt | wt | wt | n.a |
23 | M | 64 | SRL | Apical | P | 32 | M | ADC | Well differentiated ADC | wt | wt | wt | 3 |
24 | F | 53 | SLL | Apico-posterior | M | 24 | NS | ADC | Well differentiated ADC | del ex 19 | wt | wt | < 1 |
25 | F | 62 | IRL | Posterior | P | 27 | M | ADC | Well differentiated ADC | wt | wt | wt | < 1 |