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Table 1 Patient and procedural details

From: Dynamic changes of angiopoietins and endothelial nitric oxide supply during fluid resuscitation for major gyn-oncological surgery: a prospective observation

Parameter

Median (25th and 75th percentile)

Patient details:

 n

30

 Age (years)

70 (56–75)

 Body mass index (kg/m2)

27.3 (22.5–31.2)

 Diagnosed with ovarian cancer (n [%])

26 (87)

 Diagnosed with carcinoma of the cervix uteri (n [%])

1 (3)

 Diagnosed with endometrial carcinoma (n [%])

1 (3)

 Diagnosed with uterine leiomyoma (n [%])

1 (3)

 Diagnosed with ovarian granulosa cell tumor (n [%])

1 (3)

 Received neoadjuvant oncostatic chemotherapy (n [%])

11 (37)

Procedural details:

 Duration of surgery (min)

429 (293–542)

 Duration of anesthesia (min)

595 (446–689)

 Duration of mechanical ventilation (min)

1095 (604–1355)

 Postoperative ICU therapy (n [%])

27 (90)

 Length of stay in ICU (h)

40 (18–72)

 Intraop. fluid intake (mL/kg*h)

12.8 (9.7–15.4)

 Postop. fluid balance (mL)

6710 (4113–9271)

 Intraop. urine output (mL/h)

114 (78–189)

 Numbers of crystalloid infusion solution à 500 mL

14 (10–18)

 Numbers of colloid infusion solution à 500 mL

1.5 (0.75–2)

 Estimated intraop. blood loss (mL/h)

83.8 (42.6–134)

 Patients with packed red blood cell (PRBC) transfusion (n [%])

16 (53)

 Of those: numbers of PRBC units transfused

2 (2–4)

 Numbers of fresh frozen plasma units transfused

0 (0–4)

 Numbers of platelet concentrate units transfused

0 (0–0)

 Max. norepinephrine dosage (µg/kg*min)

0.09 (0.06–0.15)

 Max. dobutamine dosage (µg/kg*min)

0 (0–0)

 Postop. serum lactate (mmol/l)

1.1 (0.92–1.28)

 Length of stay in hospital (days)

25 (14–31)

 Intrahospital mortality (%)

0