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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: C-reactive protein derived from perivascular adipose tissue accelerates injury-induced neointimal hyperplasia

Fig. 3

Macrophage infiltration was enhanced in CRPTG adipose tissue in situ and the effect of CRP on the adhesion of macrophage. a Immunohistochemical staining of adipose tissue from WT and CRPTG mice for the macrophage marker CD68 and adipocyte marker TIP47. Representative images and quantitative comparisons of CD68+ cells (n = 6) are shown. Scale bar, 100 μm. b Representative flow cytometric analysis of CD11b + macrophages in vascular stromal fraction isolated from adipose tissue. c Comparison of the expression of inflammatory cytokines between wild-type and CRPTG in perivascular adipose tissue examined by QPCR *P < 0.05 versus wild-type mice. d The effect of recombinant CRP on the adhesion rate of human PMBCs. *P < 0.05 versus 0 μg/mL CRP. e The effect of CRP on the adhesion rate of THP-1 cell-derived macrophages. *P < 0.05 versus BSA control. #P < 0.05 versus 10 μg/mL CRP. Data represent mean ± SEM (n = 6)

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