Fig. 2
From: Role of IL-24 in the mucosal remodeling of children with coeliac disease
Effect of IL-1β, TNF-α, TGF-β and IL-17 treatment on the expression of IL19, IL20, IL24 and their receptors. The mRNA expression of IL19, IL20, IL24, IL20RA, IL20RB and IL22RA was determined by real-time RT-PCR in comparison with RPLP0 as internal control. Heat maps illustrate the mean fold change in relative expression of the examined genes after different treatments in FHs74Int cells (a), pdMFs (b) and PBMCs of children with CD (f) compared to vehicle controls (n = 6). Graphs of individual measurements can be found in Additional files 3, 4, 5, 6, 7. The mRNA expression of IL19 (c), IL20 (d) and IL24 (e) was determined in the PBMCs of 8–8 children with CD and controls, respectively. Results are presented as mean ± SD. ND: not detectable; *p < 0.05 vs. control (Mann–Whitney U-test)