Whole transcriptional analysis identifies markers of B, T and plasma cell signaling pathways in the mesenteric adipose tissue associated with Crohn’s disease

Table 2 List of top genes modulated in the mesenteric adipose tissue of Crohn’s disease

	Fold change CD vs. CTR	Adjusted p value	Gene name
MIR650^a	23.45	0.01	microRNA 650
FAM30A^a	22.50	0.01	Family with sequence similarity 30 member A
IGLL5^a	17.95	0.01	Immunoglobulin lambda-like polypeptide 5
MZB1^a	17.06	0.01	Marginal zone B and B1 cell-specific protein
CD79A^a	14.64	0.01	CD79a molecule, immunoglobulin-associated alpha
POU2AF1^a	13.99	0.02	POU class 2 associating factor 1
FCRL5^a	13.28	0.04	Fc receptor-like 5
JCHAIN^a	12.03	0.01	Joining chain of multimeric IgA and IgM
DERL3^a	8.35	0.01	Derlin 3
CYP4F35P	7.90	0.01	Cytochrome P450, family 4, subfamily F, polypeptide 35, pseudogene
SDC1^a	7.54	0.04	syndecan 1 (CD138)
ANKRD36BP2	7.09	0.01	Ankyrin repeat domain 36B pseudogene 2
CCL11	5.67	0.05	Chemokine (C-C motif) ligand 11
PIM2^a	4.52	0.04	Pim-2 oncogene
MEI1^a	4.26	0.05	Meiosis inhibitor 1
FAM46C	3.86	0.05	Family with sequence similarity 46, member C
PAPPA	− 4.31	0.01	Pregnancy-associated plasma protein A, pappalysin 1

ISSN: 1479-5876