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Table 2 List of top genes modulated in the mesenteric adipose tissue of Crohn’s disease

From: Whole transcriptional analysis identifies markers of B, T and plasma cell signaling pathways in the mesenteric adipose tissue associated with Crohn’s disease

  Fold change CD vs. CTR Adjusted p value Gene name
MIR650a 23.45 0.01 microRNA 650
FAM30Aa 22.50 0.01 Family with sequence similarity 30 member A
IGLL5a 17.95 0.01 Immunoglobulin lambda-like polypeptide 5
MZB1a 17.06 0.01 Marginal zone B and B1 cell-specific protein
CD79Aa 14.64 0.01 CD79a molecule, immunoglobulin-associated alpha
POU2AF1a 13.99 0.02 POU class 2 associating factor 1
FCRL5a 13.28 0.04 Fc receptor-like 5
JCHAINa 12.03 0.01 Joining chain of multimeric IgA and IgM
DERL3a 8.35 0.01 Derlin 3
CYP4F35P 7.90 0.01 Cytochrome P450, family 4, subfamily F, polypeptide 35, pseudogene
SDC1a 7.54 0.04 syndecan 1 (CD138)
ANKRD36BP2 7.09 0.01 Ankyrin repeat domain 36B pseudogene 2
CCL11 5.67 0.05 Chemokine (C-C motif) ligand 11
PIM2a 4.52 0.04 Pim-2 oncogene
MEI1a 4.26 0.05 Meiosis inhibitor 1
FAM46C 3.86 0.05 Family with sequence similarity 46, member C
PAPPA − 4.31 0.01 Pregnancy-associated plasma protein A, pappalysin 1
  1. CD Crohn’s disease, CTR control
  2. aEncoding genes of plasma cell function