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Fig. 10 | Journal of Translational Medicine

Fig. 10

From: Telocytes inhibited inflammatory factor expression and enhanced cell migration in LPS-induced skin wound healing models in vitro and in vivo

Fig. 10

EGF mRNA levels in TCs after LPS stimulation and the Schematic representation of the working model. a EGF mRNA levels in TCs after LPS stimulation. *P < 0.05 compared with vehicle. Schematic representation of the working model. b Co-culture with TCs lead to up-regulation of migration in HaCaTs and HDMECs, and down-regulation of apoptosis and death ratios of HaCaTs treated with LPS. ROS contents and inflammatory factors mRNA levels were elevated in LPS induced HaCaTs, HDMECs and L929 inflammation cell models with TCs treatment, which might provide the possible mechanism underlying the role of TCs in wound healing

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