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Table 1 Clinical characteristics of the study participants

From: Identifying genetic variants underlying medication-induced osteonecrosis of the jaw in cancer and osteoporosis: a case control study

 

BRONJ total cases (n = 38)

BRONJ cancer cases (n = 13)

BRONJ osteoporosis cases (n = 25)

Normal controls (n = 90)

Age, years

79.9 ± 11.7

60.1 ± 8.7

76.6 ± 8.8

41.1 ± 7.2

Males

8 (21%)

7 (53.8%)

2 (8.0%)

47 (52.2%)

Diagnosed condition resulting in BP prescription

   

–

 Cancer

13 (34.2%)

13 (100%)

0 (0%)

 

  Breast cancer

6 (46.2%)

6 (46.2%)

–

 

  Multiple myeloma

5 (38.5%)

5 (38.5%)

–

 

  Prostate cancer

2 (15.4%)

2 (15.4%)

–

 

 Osteoporosis

25 (65.7%)

–

25 (100%)

 

BP

   

–

 Zoledronate

11 (29.0%)

8 (61.5%)

3 (12.0%)

 

 Alendronate

10 (26.0%)

–

10 (40.0%)

 

 Residronate

5 (13.2%)

–

5 (20.0%)

 

 Pamidronate

3 (7.9%)

3 (23.1%)

–

 

 Ibandronate

2 (5.3%)

–

2 (8.0%)

 

 Zoledronate/ibandronate

1 (2.6%)

1 (7.7%)

–

 

 Unknown

6 (15.8%)

1 (7.7%)

5 (20.0%)

 

Duration of BP treatment before BRONJ occurrence, months

42.7 ± 46.3

18.1 ± 13.9

56.0 ± 52.3

–

  1. Data are mean ± SD or n (%) values