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Table 2 Definition of long-term neurocognitive outcomes at ~ 2 years of age

From: Mining multi-site clinical data to develop machine learning MRI biomarkers: application to neonatal hypoxic ischemic encephalopathy

i. Continuously-valued outcome

Numerical domain scores

BSID-III (Bayley Scale of Infant Development, Version III)

Cognitive (ranging 50–150)

Language (ranging 50–150)

Motor (ranging 50–150)

ii. Binary-valued outcome

Definition

Developmental delay

YES (1) if BSID-III ≤ 85 in any domain OR any documentation by a physician that there is a significant delay in motor, cognitive, or language development that requires intervention; otherwise NO (0)

Cerebral palsy

As documented in the EHR by the medical provider

Motor impairment

YES (1) if BSID-III ≤ 85 in the motor domain OR any noted motor abnormality documented in the EHR by a medical provider; or NO (0)

Visual/hearing impairment

As documented in the EHR by a medical provider