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Table 1 Baseline characteristics of patients in the development and validation cohorts

From: A prospective study of acute kidney injury in the intensive care unit: development and validation of a risk prediction model

Variables Development Cohort
(n = 656)
Validation Cohort
(n = 280)
P-value
Age, years, mean (SD) 58 (18) 57 (18) 0.445
Male, n (%) 445 (68) 193 (69) 0.742
SCr baseline measures, μmol/L, median (IQR) 85 (62–131) 80 (58–118) 0.264
Age > 70, n (%) 173 (26) 66 (24) 0.547
Hypertension, n (%) 213 (32) 97 (35) 0.518
Diabetes, n (%) 120 (18) 43 (15) 0.278
Chronic kidney disease, n (%) 50 (8) 24 (9) 0.622
Chronic liver disease, n (%) 73 (11) 35 (13) 0.547
Chronic pulmonary disease, n (%) 144 (22) 68 (24) 0.435
Coronary heart disease, n (%) 42 (6) 20 (7) 0.677
Cancer, n (%) 143 (22) 63 (23) 0.813
Acute pancreatitis, n (%) 75 (11) 36 (13) 0.537
Severe empyrosis, n (%) 8 (1) 4 (1) 0.795
Trauma, n (%) 162 (25) 56 (20) 0.120
Cardiac failure, n (%) 196 (30) 74 (26) 0.286
Respiratory failure, n (%) 310 (47) 122 (44) 0.300
Sepsis, n (%) 154 (23) 61 (22) 0.574
Shock, n (%) 273 (42) 122 (44) 0.579
Cardiopulmonary arrest, n (%) 52 (8) 15 (5) 0.163
Anemia, n (%) 530 (81) 218 (78) 0.305
Hypoproteinemia, n (%) 456 (70) 197 (70) 0.797
pH ≤ 7.30, n (%) 104 (16) 40 (14) 0.543
CK > 1000 U/L, n (%) 200 (30) 77 (28) 0.359
Nephrotoxin exposure, n (%) 131 (20) 69 (25) 0.110
Major surgery, n (%) 408 (62) 180 (64) 0.545
Blood transfusion, n (%) 330 (50) 133 (48) 0.432
Receiving RRT, n (%) 113 (17) 50 (18) 0.816
Mortality, n (%) 213 (32) 84 (30) 0.457