Table 6 miR expression changes in peripheral blood PFP during the 1st month of chemotherapy

Whole cohort

miR-128-3p

− 2.86 (3.6*10⁻⁷)

− 3.15 (3.87*10⁻⁷)

− 3.60 (7.77*10⁻¹⁰)

miR-181a-5p

− 1.33 (3.12*10⁻²)

− 0.93 (NS)

− 2.08 (1.01*10⁻³)

miR-181b-5p

− 1.75 (1.48*10⁻²)

− 2.39 (2.05*10⁻³)

− 2.76 (8.78*10⁻⁵)

miR-222-3p

− 1.25 (1.66*10⁻²)

− 1.03 (NS)

− 1.94 (2.09*10⁻⁴)

Karyotype: normal^a

miR-128-3p

− 2.49 (2.87*10⁻³)

− 2.29 (3.09*10⁻²)

− 2.99 (4.15*10⁻⁴)

miR-181a-5p

− 2.58 (2.87*10⁻³)

− 1.79 (NS)

− 3.82 (1.16*10⁻⁵)

miR-181b-5p

− 2.72 (2.87*10⁻³)

− 3.44 (1.51*10⁻³)

− 4.50 (7.63*10⁻⁷)

miR-222-3p

− 1.23 (NS)

− 0.98 (NS)

− 2.45 (2.41*10⁻³)

Karyotype: t(12;21)

miR-128-3p

− 4.33 (2.20*10⁻⁸)

− 4.62 (1.74*10⁻⁸)

− 4.42 (2.12*10⁻⁸)

miR-181a-5p

− 1.72 (NS)

− 0.71 (NS)

− 1.13 (NS)

miR-181b-5p

− 2.49 (4.11*10⁻²)

− 2.42 (NS)

− 2.02 (NS)

miR-222-3p

− 2.15 (1.16*10⁻²)

− 1.59 (NS)

− 1.82 (3.39*10⁻²)

Karyotype: hyperdiploid

miR-128-3p

− 1.39 (NS)

− 2.21 (NS)

− 3.31 (NS)

miR-181a-5p

− 1.16 (NS)

− 0.16 (NS)

− 1.01 (NS)

miR-181b-5p

0.82 (NS)

− 0.98 (NS)

− 1.42 (NS)

miR-222-3p

0.08 (NS)

− 0.20 (NS)

− 1.47 (NS)