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Table 3 Multivariate Cox logistic regression analysis of OS in TCGA and FUSCC cohort

From: Prognostic implications of Aquaporin 9 expression in clear cell renal cell carcinoma

Covariates TCGA FUSCC
HR 95% CI p value HR 95% CI p value
Age 1.297 0.849–1.982 0.229 1.011 0.998–1.025 0.094
pT stage (ref. T1–T2) 1.692 0.740–3.871 0.213 1.692 1.011–2.830 0.045
pN stage (ref. N0) 1.488 0.740–2.993 0.265 1.837 1.173–2.877 0.008
pM stage (ref. M0) 2.629 1.578–4.381 < 0.001 1.895 1.137–3.159 0.014
AJCC stage (ref. I–II) 1.279 0.510–3.207 0.600 3.553 1.814–6.956 < 0.001
ISUP grade (ref. 1–2) 1.509 0.916–2.486 0.106 1.751 1.196–2.562 0.004
AQP9 expression (ref. negative) 1.707 1.067–2.731 0.026 1.514 1.050–2.183 0.026
  1. p value less than 0.05 are in italics
  2. OS overall survival, TCGA: The Cancer Genome Atlas, FUSCC Fudan University Shanghai Cancer Center