Table 3 Multivariate Cox logistic regression analysis of OS in TCGA and FUSCC cohort
From: Prognostic implications of Aquaporin 9 expression in clear cell renal cell carcinoma
Covariates | TCGA | FUSCC | ||||
|---|---|---|---|---|---|---|
HR | 95% CI | p value | HR | 95% CI | p value | |
Age | 1.297 | 0.849–1.982 | 0.229 | 1.011 | 0.998–1.025 | 0.094 |
pT stage (ref. T1–T2) | 1.692 | 0.740–3.871 | 0.213 | 1.692 | 1.011–2.830 | 0.045 |
pN stage (ref. N0) | 1.488 | 0.740–2.993 | 0.265 | 1.837 | 1.173–2.877 | 0.008 |
pM stage (ref. M0) | 2.629 | 1.578–4.381 | < 0.001 | 1.895 | 1.137–3.159 | 0.014 |
AJCC stage (ref. I–II) | 1.279 | 0.510–3.207 | 0.600 | 3.553 | 1.814–6.956 | < 0.001 |
ISUP grade (ref. 1–2) | 1.509 | 0.916–2.486 | 0.106 | 1.751 | 1.196–2.562 | 0.004 |
AQP9 expression (ref. negative) | 1.707 | 1.067–2.731 | 0.026 | 1.514 | 1.050–2.183 | 0.026 |