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Table 2 Multivariate Cox logistic regression analysis of PFS in TCGA and FUSCC cohort

From: Prognostic implications of Aquaporin 9 expression in clear cell renal cell carcinoma

Covariates

TCGA

FUSCC

HR

95% CI

p value

HR

95% CI

p value

Age

–

–

–

1.008

0.996–1.020

0.207

Gender (ref. male)

0.563

0.157–2.022

0.379

–

–

–

pT stage (ref. T1–T2)

0.467

0.093–2.340

0.354

1.782

1.084–2.930

0.023

pN stage (ref. N0)

–

–

–

1.937

1.250–3.001

0.003

pM stage (ref. M0)

2.690

1.034–7.000

0.043

1.763

1.104–2.813

0.018

AJCC stage (ref. I–II)

4.283

0.703–26.095

0.115

2.425

1.292–4.552

0.006

ISUP grade (ref. 1–2)

2.269

0.817–6.301

0.116

1.812

1.330–2.471

< 0.001

AQP9 expression (ref. negative)

3.443

1.058–11.205

0.040

1.714

1.258–2.335

0.001

  1. p value less than 0.05 are in italics
  2. PFS progression-free survival, TCGA The Cancer Genome Atlas, FUSCC Fudan University Shanghai Cancer Center