From: Prognostic implications of Aquaporin 9 expression in clear cell renal cell carcinoma
Covariates | TCGA | FUSCC | ||||
---|---|---|---|---|---|---|
HR | 95% CI | p value | HR | 95% CI | p value | |
Age | – | – | – | 1.008 | 0.996–1.020 | 0.207 |
Gender (ref. male) | 0.563 | 0.157–2.022 | 0.379 | – | – | – |
pT stage (ref. T1–T2) | 0.467 | 0.093–2.340 | 0.354 | 1.782 | 1.084–2.930 | 0.023 |
pN stage (ref. N0) | – | – | – | 1.937 | 1.250–3.001 | 0.003 |
pM stage (ref. M0) | 2.690 | 1.034–7.000 | 0.043 | 1.763 | 1.104–2.813 | 0.018 |
AJCC stage (ref. I–II) | 4.283 | 0.703–26.095 | 0.115 | 2.425 | 1.292–4.552 | 0.006 |
ISUP grade (ref. 1–2) | 2.269 | 0.817–6.301 | 0.116 | 1.812 | 1.330–2.471 | < 0.001 |
AQP9 expression (ref. negative) | 3.443 | 1.058–11.205 | 0.040 | 1.714 | 1.258–2.335 | 0.001 |