Fig. 5
From: Prognostic implications of Aquaporin 9 expression in clear cell renal cell carcinoma
Functional annotations and predicted signaling pathways. a The PPI network of AQP9 was constructed. A network of AQP9 and its co-expression genes was set up visually. b Functional enrichment analyses of a total of 11 involved genes were performed and visualized in bubble chart. Significant genes were significantly involved in polyol transport, defense response, immune response, and markedly participated in plasma membrane, integral to membrane, intrinsic to membrane and plasma membrane part. c Functional annotation using ClueGO indicated that changes in the biological processes of the AQP9 were significantly associated with the transport, integral component of membrane and endomembrane system