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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Prognostic implications of Aquaporin 9 expression in clear cell renal cell carcinoma

Fig. 2

Transcriptional expressions of AQP9 significantly correlated with advanced clinicopathological parameters and poor survival outcomes in ccRCC patients from TCGA cohort. a Transcriptional expression of AQP9 was significantly correlated with AJCC stages, patients who were in more advanced stages tended to express higher mRNA expression of AQP9. b Transcriptional expression of AQP9 was significantly correlated with ISUP grade, patients who were in more advanced grade score tended to express elevated mRNA expression of AQP9. Highest mRNA expressions of AQP9 were found in stage 4 or grade 4. *p < 0.05, **p < 0.01, ***p < 0.001. c Survival analysis in Kaplan–Meier method indicated that AQP9 was significantly correlated with shorter PFS (p = 0.009). d Survival curves suggested that patients with elevated AQP9 mRNA levels showed poorer OS in 533 included ccRCC patients (p < 0.001)

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