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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Decreased plasma phospholipid concentrations and increased acid sphingomyelinase activity are accurate biomarkers for community-acquired pneumonia

Fig. 5

Selection of lipid biomarkers that correlate with resolution of CAP. A plot of linear fitting slope (y-axis, LFS) vs. 1-normalized distance to fitting (x-axis, NDF) was used to identify lipid analytes (a) and metabolic indicators (b) that correlate best with resolution of CAP. (C-H) Concentrations across the time course for CRP (c), PCT (d), the 2 best correlating lipids, lysoPCaC16:1 (e), lysoPCaC16:0 (f), and the 2 best correlating metabolic indicators, total lysoPC (g), lysoPCaC16:0/lysoPCaC16:1 (h). *p < 0.05, **p < 0.01, ***p < 0.001 (Mann–Whitney U test for paired comparisons, Kruskal–Wallis H-test for CAP d1 through CAP f2). Metabolite abbreviation: lysoPC, lysophosphatidylcholines

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