From: Prognostic nomogram for bladder cancer with brain metastases: a National Cancer Database analysis
Clinical variables | Description | Values |
---|---|---|
Age | Age of the patient at diagnosis | < 65 years or ≥ 65 years |
Sex | The gender of the patient | Male or female |
Race | The primary race of the person | White, black or others |
Grade | Describes the tumor’s resemblance to normal tissue (coded according to ICD-O-3) | Well differentiated, poorly differentiated or Unknown |
Tumor_Stage | NCDB analytic stage identifies the clinically or pathologically determined size and/or extension of the primary tumor (cT) as defined by the American Joint Committee on Cancer (AJCC) | High (Stage III, IV) or low (Stage I, II) |
Lymph_nodes | Identifies the clinically-determined absence or presence of regional lymph node metastasis and describes the corresponding extent as defined by the American Joint Committee on Cancer (AJCC) | Yes, no or unknown |
Histology | Indicate the pathological histology of tumor cells (coded according to ICD-O-3) | Transitional cell carcinoma, papillary urothelial carcinoma, small cell carcinoma or others |
Lymph_Vas_invasion | Indicate the presence or absence of tumor cells in lymphatic channels (other than lymph nodes) or blood vessels within the primary tumor as noted microscopically by the pathologist | Yes, no or unknown |
Met_Bone | Indicate the presence of distant involvement of bone at the time of diagnosis | Yes or no |
Met_Liver | Indicate the presence of distant involvement of liver at the time of diagnosis | Yes or no |
Met_Lung | Indicate the presence of distant involvement of lung at the time of diagnosis | Yes or no |
Surgery_Primary | Records the surgical procedure and approach performed to the primary site | Minimal invasive surgery, non-minimal invasive surgery or no surgery |
Chemotherapy | Records of chemotherapy administrated as first course treatment | Yes or no |
Radiation_Therapy | Anatomic target volume is directed at tumors lying within the substance of brain or its meninges | Yes or no |
Paliative_Care | Any care provided an effort to palliate or alleviate symptoms | Yes or no |
Brain_Confined_Met | Indicate the presence of distant involvement of brain only or brian combined with other organs at the time of diagnosis | Brain confined or non-brain confined |
CDCC_Score | Charlson/Deyo Score, a weighted score derived from the sum of the scores for each of the comorbid conditions listed in the Charlson Comorbidity Score Mapping Table (source http://dx.doi.org/10.17632/nn6y58v8vv.1#file-a72735e9-15b5-4a10-aef5-deddad2463e8) | 0–3 |
Surgery_Met | Records the surgical removal of distant lymph nodes or other tissues or organs beyond the primary site | Yes or no |