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Table 1 Description of clinical characteristics and their values

From: Prognostic nomogram for bladder cancer with brain metastases: a National Cancer Database analysis

Clinical variables

Description

Values

Age

Age of the patient at diagnosis

< 65 years or ≥ 65 years

Sex

The gender of the patient

Male or female

Race

The primary race of the person

White, black or others

Grade

Describes the tumor’s resemblance to normal tissue (coded according to ICD-O-3)

Well differentiated, poorly differentiated or Unknown

Tumor_Stage

NCDB analytic stage identifies the clinically or pathologically determined size and/or extension of the primary tumor (cT) as defined by the American Joint Committee on Cancer (AJCC)

High (Stage III, IV) or low (Stage I, II)

Lymph_nodes

Identifies the clinically-determined absence or presence of regional lymph node metastasis and describes the corresponding extent as defined by the American Joint Committee on Cancer (AJCC)

Yes, no or unknown

Histology

Indicate the pathological histology of tumor cells (coded according to ICD-O-3)

Transitional cell carcinoma, papillary urothelial carcinoma, small cell carcinoma or others

Lymph_Vas_invasion

Indicate the presence or absence of tumor cells in lymphatic channels (other than lymph nodes) or blood vessels within the primary tumor as noted microscopically by the pathologist

Yes, no or unknown

Met_Bone

Indicate the presence of distant involvement of bone at the time of diagnosis

Yes or no

Met_Liver

Indicate the presence of distant involvement of liver at the time of diagnosis

Yes or no

Met_Lung

Indicate the presence of distant involvement of lung at the time of diagnosis

Yes or no

Surgery_Primary

Records the surgical procedure and approach performed to the primary site

Minimal invasive surgery, non-minimal invasive surgery or no surgery

Chemotherapy

Records of chemotherapy administrated as first course treatment

Yes or no

Radiation_Therapy

Anatomic target volume is directed at tumors lying within the substance of brain or its meninges

Yes or no

Paliative_Care

Any care provided an effort to palliate or alleviate symptoms

Yes or no

Brain_Confined_Met

Indicate the presence of distant involvement of brain only or brian combined with other organs at the time of diagnosis

Brain confined or non-brain confined

CDCC_Score

Charlson/Deyo Score, a weighted score derived from the sum of the scores for each of the comorbid conditions listed in the Charlson Comorbidity Score Mapping Table (source http://dx.doi.org/10.17632/nn6y58v8vv.1#file-a72735e9-15b5-4a10-aef5-deddad2463e8)

0–3

Surgery_Met

Records the surgical removal of distant lymph nodes or other tissues or organs beyond the primary site

Yes or no