From: Placental mitochondrial DNA content is associated with childhood intelligence
Covariates | Multi variable model | ||
---|---|---|---|
Change in IQ | 95% CI | p-value | |
Covariates total intelligence quotient | Â | Â | Â |
Girls | − 2.57 | − 5.32 to 0.17 | 0.07 |
Birth weight, + IQR | 1.81 | − 0.36 to 3.98 | 0.10 |
Gestational age, + IQR | 0.17 | − 1.67 to 2.00 | 0.86 |
Birth year, + 1 year | − 1.99 | − 3.03 to − 0.96 | 0.0002 |
Peripheral cord insertion | 1.31 | − 1.39 to 4.00 | 0.34 |
Age at measurement, + 1 year | − 1.50 | − 3.06 to 0.06 | 0.06 |
High parental educational level | 6.99 | 4.19 to 9.79 | <Â 0.0001 |
Neigbourhood household income, + IQR | − 0.42 | − 2.10 to 1.25 | 0.62 |
Maternal smoking during pregnancy | − 1.46 | − 6.21 to 3.29 | 0.55 |
Urban environment, + IQR | 2.40 | − 0.03 to 4.83 | 0.05 |
Covariates verbal intelligence quotient | Â | Â | Â |
Girls | − 3.52 | − 6.24 to − 0.79 | 0.01 |
Birth weight, + IQR | 1.78 | − 0.37 to 3.94 | 0.11 |
Gestational age, + IQR | − 0.13 | − 1.88 to 1.62 | 0.88 |
Birth year, + 1 year | − 2.21 | − 3.15 to − 1.26 | < 0.0001 |
Peripheral cord insertion | 0.87 | − 1.79 to 3.54 | 0.52 |
Age at measurement, + 1 year | − 1.83 | − 3.26 to − 0.40 | 0.01 |
High parental educational level | 6.76 | 4.14 to 9.38 | <Â 0.0001 |
Neigbourhood household income, + IQR | − 0.98 | − 2.55 to 0.58 | 0.22 |
Maternal smoking during pregnancy | − 2.29 | − 6.73 to 2.14 | 0.31 |
Urban environment, + IQR | 1.54 | − 0.77 to 3.84 | 0.19 |
Covariates performance intelligence quotient | Â | Â | Â |
Girls | − 1.50 | − 4.48 to 1.47 | 0.32 |
Birth weight, + IQR | 0.99 | − 1.31 to 3.28 | 0.40 |
Gestational age, +IQR | 0.51 | − 1.41 to 2.43 | 0.60 |
Birth year, + 1 year | − 1.18 | − 2.27 to − 0.09 | 0.03 |
Peripheral cord insertion | 0.56 | − 2.28 to 3.39 | 0.70 |
Age at measurement, + 1 year | − 0.71 | − 2.35 to 0.93 | 0.40 |
High parental educational level | 5.57 | 2.65 to 8.49 | 0.0003 |
Neigbourhood household income, + IQR | 0.14 | − 1.61 to 1.88 | 0.88 |
Maternal smoking during pregnancy | − 0.09 | − 5.04 to 4.86 | 0.91 |
Urban environment, + IQR | 2.59 | 0.08 to 5.11 | 0.05 |