Fig. 5

Rapamycin promotes apoptosis in primary pituitary adenoma and meningioma cells of PAM: a Flow cytometry revealing that the apoptosis rate of primary pituitary adenoma cells of PAM increased following treatment with rapamycin treatment in a dose-dependent manner for 48 h and 72 h; b Flow cytometry revealing that the apoptosis rate of primary pituitary adenoma cells increased following treatment with rapamycin 2 nM for 72 h; c Flow cytometry revealing that the FAS concentration of primary pituitary adenoma cells increased following treatment with rapamycin 2 nM for 72 h; d Flow cytometry revealing that the apoptosis rate of primary meningioma cells of PAM increased following treatment with rapamycin treatment in a dose-dependent manner for 48 h and 72 h; e Flow cytometry revealing that the apoptosis rate of primary meningioma cells increased following treatment with rapamycin 10 nM for 72 h; f Flow cytometry revealing that the FAS concentration of primary pituitary adenoma cells increased following treatment with rapamycin 10 nM for 72 h* P < 0.05, **P < 0.01, ***P < 0.001