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Table 9 Differences in microbial metabolites between rectal cancer and sigmoid cancer

From: Analysis of prognosis, genome, microbiome, and microbial metabolome in different sites of colorectal cancer

 

Rectal cancer

Sigmoid cancer

p-value

Cases, n

15

13

–

Palmitoleic acid (ng/mg)

1033.65 ± 1074.68

315.39 ± 529.27

0.038

1H-Indole-3-acetamide (ng/mg)

96.36 ± 69.24

46.84 ± 22.90

0.021

Indole (ng/mg)

1876.80 ± 2381.81

494.15 ± 473.88

0.050

Citraconic acid (ng/mg)

21.10 ± 19.11

9.42 ± 3.63

0.040

Erucic acid (ng/mg)

53.32 ± 52.14

19.54 ± 12.96

0.032

Fumaric acid (ng/mg)

141.11 ± 129.74

51.75 ± 47.20

0.027

Hippuric acid (ng/mg)

1182.46 ± 833.71

641.37 ± 369.39

0.040

Hydrocinnamic acid (ng/mg)

217.46 ± 243.41

57.57 ± 135.79

0.046

Nicotinic acid (ng/mg)

47.59 ± 50.16

16.86 ± 12.71

0.041

Oxoglutaric acid (ng/mg)

795.68 ± 897.00

90.56 ± 81.18

0.009

Acetic acid (ng/mg)

26,194.35 ± 21,949.09

11,351.32 ± 13,454.89

0.044

m-Hydroxyhippuric acid (ng/mg)

500.98 ± 711.27

1413.65 ± 1354.92

0.031

  1. The number of nanogram metabolites per milligram of faeces were analysed by GC-TOFMS analysis. The table showed the content of microbial metabolites with statistical differences between the two groups (Kruskal test, p-value < 0.05)