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Table 9 Differences in microbial metabolites between rectal cancer and sigmoid cancer

From: Analysis of prognosis, genome, microbiome, and microbial metabolome in different sites of colorectal cancer

  Rectal cancer Sigmoid cancer p-value
Cases, n 15 13
Palmitoleic acid (ng/mg) 1033.65 ± 1074.68 315.39 ± 529.27 0.038
1H-Indole-3-acetamide (ng/mg) 96.36 ± 69.24 46.84 ± 22.90 0.021
Indole (ng/mg) 1876.80 ± 2381.81 494.15 ± 473.88 0.050
Citraconic acid (ng/mg) 21.10 ± 19.11 9.42 ± 3.63 0.040
Erucic acid (ng/mg) 53.32 ± 52.14 19.54 ± 12.96 0.032
Fumaric acid (ng/mg) 141.11 ± 129.74 51.75 ± 47.20 0.027
Hippuric acid (ng/mg) 1182.46 ± 833.71 641.37 ± 369.39 0.040
Hydrocinnamic acid (ng/mg) 217.46 ± 243.41 57.57 ± 135.79 0.046
Nicotinic acid (ng/mg) 47.59 ± 50.16 16.86 ± 12.71 0.041
Oxoglutaric acid (ng/mg) 795.68 ± 897.00 90.56 ± 81.18 0.009
Acetic acid (ng/mg) 26,194.35 ± 21,949.09 11,351.32 ± 13,454.89 0.044
m-Hydroxyhippuric acid (ng/mg) 500.98 ± 711.27 1413.65 ± 1354.92 0.031
  1. The number of nanogram metabolites per milligram of faeces were analysed by GC-TOFMS analysis. The table showed the content of microbial metabolites with statistical differences between the two groups (Kruskal test, p-value < 0.05)