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Table 4 Clinical characteristics of left-sided and right-sided CRC in the SEER database

From: Analysis of prognosis, genome, microbiome, and microbial metabolome in different sites of colorectal cancer

 

RS

LS

Total

Median age (min–max)

71 (13–108)

63 (11–106)

67 (11–108)

Gender

 Male

22.99

27.58

50.57

 Female

27.64

21.79

49.43

Race (%)

 White

40.65

38.82

79.47

 Black

6.52

4.99

11.51

 Asian

2.84

4.73

7.57

 Other

0.61

0.85

1.46

Stage at presentation (%)

 Stage 0

0.61

0.50

1.11

 Stage I

10.67

11.23

21.90

 Stage II

16.67

13.66

30.32

 Stage III

15.53

17.53

33.06

 Stage IV

7.14

6.46

13.60

Histologic subtype (%)

 Adenocarcinoma

43.49

46.04

89.54

 Mucinous adenocarcinoma

5.67

2.69

8.37

 Other

1.45

0.64

2.10

Histologic grade (%)

 Well differentiated

4.33

4.21

8.54

 Moderately differentiated

33.63

37.77

71.40

 Poorly differentiated

10.85

6.58

17.43

 Undifferentiated

1.81

0.82

2.63

Adequate lymph node examination (more than 12 nodes) (%)

 Yes

41.94

34.62

76.56

 No

8.57

14.60

23.17

 Missing data

0.11

0.16

0.27

Type of surgery (%)

 Local excision

0.06

0.39

0.45

 Partial colectomy

9.93

34.68

44.60

 Hemicolectomy

39.34

8.43

47.77

 Total colectomy

0.70

4.34

5.04

 Other colectomy

0.55

1.38

1.94

 No surgery

0.04

0.15

0.19

Chemotherapy (%)

 Yes

15.59

24.48

40.07

 No/unknown

35.03

24.90

59.93

Radiation therapy (%)

 Yes

0.53

12.26

12.79

 No/unknown

50.09

37.12

87.21

  1. All patients diagnosed with colon and rectal adenocarcinoma from 2006 to 2015 in the SEER database were included. Right-sided (RS) CRC includes cancers located in the cecum, ascending colon, and transverse colon, and left-sided (LS) CRC includes those located in the descending colon, sigmoid colon, and rectum. A total of 179,323 CRC patients were included after screening