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Table 1 Clinical characteristics of CRC in different sites in the SEER database

From: Analysis of prognosis, genome, microbiome, and microbial metabolome in different sites of colorectal cancer

  Cecum Ascending colon Transverse colon Descending colon Sigmoid colon Rectum Total
Median age (min–max) 71 (15–105) 71 (15–108) 70 (13–102) 65 (16-101) 64 (11–106) 61 (14–103) 67 (11–108)
Gender (%)
 Male 9.93 8.81 4.25 3.01 13.81 10.76 50.57
 Female 12.62 10.48 4.54 2.62 11.95 7.22 49.43
Race (%)
 White 18.29 15.38 6.97 4.11 20.04 14.67 79.46
 Black 2.92 2.47 1.13 0.89 2.67 1.43 11.51
 Asian 1.09 1.19 0.56 0.55 2.61 1.57 7.57
 Other 0.25 0.25 0.13 0.08 0.45 0.31 1.46
Stage at presentation (%)
 Stage 0 0.28 0.25 0.08 0.06 0.29 0.15 1.11
 Stage I 4.69 4.25 1.72 1.03 6.02 4.18 21.90
 Stage II 6.73 6.69 3.25 1.84 7.11 4.71 30.32
 Stage III 7.23 5.77 2.53 1.87 8.39 7.27 33.06
 Stage IV 3.61 2.33 1.20 0.83 3.95 1.67 13.60
Histologic subtype (%)
 Adenocarcinoma 19.23 16.54 7.73 5.13 24.21 16.70 89.54
 Mucinous adenocarcinoma 2.59 2.20 0.88 0.42 1.30 0.97 8.37
 Other 0.73 0.55 0.18 0.08 0.25 0.31 2.10
Histologic grade (%)
 Well differentiated 1.92 1.66 0.74 0.50 2.34 1.38 8.54
 Moderately differentiated 14.89 12.73 6.01 4.17 19.75 13.85 71.40
 Poorly differentiated 4.88 4.20 1.77 0.85 3.25 2.47 17.43
 Undifferentiated 0.85 0.69 0.27 0.12 0.43 0.27 2.63
Adequate lymph node examination (more than 12 nodes) (%)
 Yes 18.68 16.59 6.67 4.20 18.47 11.95 76.56
 No 3.81 2.66 2.10 1.43 7.23 5.93 23.17
 Missing data 0.06 0.04 0.02 0.01 0.06 0.09 0.27
Type of surgery (%)
 Local excision 0.02 0.03 0.01 0.02 0.11 0.26 0.45
 Partial colectomy 3.59 2.79 3.54 1.91 20.36 12.41 44.60
 Hemicolectomy 18.39 16.05 4.90 3.48 4.24 0.72 47.77
 Total colectomy 0.29 0.22 0.19 0.15 0.51 3.69 5.04
 Other colectomy 0.24 0.18 0.14 0.08 0.52 0.79 1.94
 No surgery 0.02 0.02 0.01 0.01 0.03 0.12 0.19
Chemotherapy (%)
 Yes 7.33 5.52 2.74 2.14 9.93 12.41 40.07
 No/unknown 15.21 13.77 6.05 3.49 15.83 5.57 59.93
Radiation therapy (%)
 Yes 0.32 0.15 0.06 0.07 0.81 11.38 12.79
 No/unknown 22.23 19.14 8.73 5.56 24.95 6.60 87.21
  1. SEER*Stat software (seer.cancer.gov/seerstat) was used to access the SEER data after signing research data agreement. All patients diagnosed with colon and rectal adenocarcinoma from 2006 to 2015 were included. A total of 179,323 CRC patients were included after screening