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Table 1 Univariate and multivariate analyses for survival of adenocarcinoma patients
| Variables | Overall survival | Progression-free survival | ||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| A (univariate) | ||||
| Gender | ||||
| Male | 1.88 (0.89–3.97) | 0.094 | 2.16 (1.10–4.23) | 0.025 |
| Female | 1 | 1 | ||
| Age (years) | ||||
| ≥ 60 | 1.23 (0.60–2.54) | 0.565 | 1.12 (0.58–2.13) | 0.731 |
| < 60 | 1 | 1 | ||
| Smoking status | ||||
| Ever smokers | 1.73 (0.84–3.55) | 0.136 | 1.60 (0.84–3.04) | 0.147 |
| Never smokers | 1 | 1 | ||
| cStage | ||||
| IV | 1.05 (0.25–4.45) | 0.940 | 0.76 (0.23–2.49) | 0.658 |
| III | 1 | 1 | ||
| Tumor differentiation | ||||
| Poor | 1.90 (0.88–4.11) | 0.101 | 1.75 (0.89–3.45) | 0.103 |
| Well/moderate | 1 | 1 | ||
| Performance status | ||||
| 1–2 | 1.68 (0.64–4.41) | 0.291 | 1.97 (0.82–4.73) | 0.129 |
| 0 | 1 | 1 | ||
| B | 0.99 (0.92–1.07) | 0.818 | 0.93 (0.86–1.06) | 0.677 |
| NK | 1.01 (0.96–1.05) | 0.892 | 0.96 (0.91–1.02) | 0.645 |
| NKT | 0.87 (0.58–1.09) | 0.583 | 0.68 (0.36–1.07) | 0.328 |
| γδT | 0.94 (0.85–1.05) | 0.298 | 0.95 (0.86–1.04) | 0.295 |
| CD8+CD28+ | 0.52 (0.25–0.92) | 0.013 | 0.59 (0.29–0.96) | 0.016 |
| CD8+CD28− | 0.93 (0.79–1.12) | 0.349 | 0.98 (0.95–1.02) | 0.314 |
| CD28+/CD28− | 1.08 (0.69–1.68) | 0.735 | 1.00 (0.68–1.47) | 0.991 |
| CD4+CD25hi | 1.57 (0.88–2.46) | 0.153 | 1.96 (1.22–2.81) | 0.011 |
| B (multivariate) | ||||
| Gender | 1.92 (0.82–4.49) | 0.133 | 2.12 (0.99–4.57) | 0.055 |
| CD8+CD28+ | 0.51 (0.30–0.89) | 0.021 | 0.66 (0.37–0.93) | 0.038 |
| CD4+CD25hi | – | – | 1.53 (1.19–1.97) | 0.031 |
