Table 1 Univariate and multivariate analyses for survival of adenocarcinoma patients

A (univariate)

 Gender

  Male

1.88 (0.89–3.97)

0.094

2.16 (1.10–4.23)

  Female

1

1

 Age (years)

  ≥ 60

1.23 (0.60–2.54)

0.565

1.12 (0.58–2.13)

  < 60

1

1

 Smoking status

  Ever smokers

1.73 (0.84–3.55)

0.136

1.60 (0.84–3.04)

  Never smokers

1

1

 cStage

  IV

1.05 (0.25–4.45)

0.940

0.76 (0.23–2.49)

  III

1

1

 Tumor differentiation

  Poor

1.90 (0.88–4.11)

0.101

1.75 (0.89–3.45)

  Well/moderate

1

1

 Performance status

  1–2

1.68 (0.64–4.41)

0.291

1.97 (0.82–4.73)

  0

1

1

B

0.99 (0.92–1.07)

0.818

0.93 (0.86–1.06)

NK

1.01 (0.96–1.05)

0.892

0.96 (0.91–1.02)

NKT

0.87 (0.58–1.09)

0.583

0.68 (0.36–1.07)

γδT

0.94 (0.85–1.05)

0.298

0.95 (0.86–1.04)

CD8+CD28+

0.52 (0.25–0.92)

0.013

0.59 (0.29–0.96)

CD8+CD28−

0.93 (0.79–1.12)

0.349

0.98 (0.95–1.02)

CD28+/CD28−

1.08 (0.69–1.68)

0.735

1.00 (0.68–1.47)

CD4+CD25^hi

1.57 (0.88–2.46)

0.153

1.96 (1.22–2.81)

B (multivariate)

 Gender

1.92 (0.82–4.49)

0.133

2.12 (0.99–4.57)

 CD8+CD28+

0.51 (0.30–0.89)

0.021

0.66 (0.37–0.93)

 CD4+CD25^hi

–

–

1.53 (1.19–1.97)