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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Mild hyperthermia by MR-guided focused ultrasound in an ex vivo model of osteolytic bone tumour: optimization of the spatio-temporal control of the delivered temperature

Fig. 7

2D MR thermometry maps during MRgHIFU hyperthermia of a bone tumor mimicking model, in a plane perpendicular to the bone long axis and with the focal point positioned in the center of the cortical breakthrough. Data are shown: a Prior to HIFU sonication, bd 80 s, 160 s, and 320 s after the onset of HIFU sonication, respectively. Note the circumferential temperature elevation of the internal facet of the cortical bone (“acoustic oven effect”) and the evolution of the thermal build-up inside the medullar cavity towards a uniform distribution

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