DNA methylation exploration for ARDS: a multi-omics and multi-microarray interrelated analysis

Table 2 Relationship between methylation sites and mRNA, with AUC of methylation sites

Low expressed mRNA	Hypermethylation sites	AUC to distinguish ARDS	High expressed mRNA	Demethylation sites	AUC to distinguish ARDS
CX3CR1	cg00262061	0.89	SH3GL1	cg07830557	0.99
CX3CR1	cg03341377	0.99	SH3GL1	cg08418670	0.99
CX3CR1	cg05046858	0.87	SLC3A2	cg02838784	0.79
CX3CR1	cg24310395	0.99	SLC7A1	cg21175585	0.83
CYTIP	cg19506253	0.97	SLC7A1	cg26117398	0.77
DUSP6	cg06705834	0.66	TBC1D22B	cg08784966	0.93
DUSP6	cg06864046	0.62	TBC1D22B	cg12800266	0.95
FYN	cg00801571	0.93	TBC1D22B	cg22902977	0.74
FYN	cg01557421	0.8
FYN	cg02115050	0.7
FYN	cg02755956	0.9
FYN	cg02789394	0.98
FYN	cg02816367	0.72
FYN	cg04657000	0.94
FYN	cg07725064	0.95
FYN	cg11412876	0.61
FYN	cg12636607	0.92
FYN	cg17076443	0.6
FYN	cg17587997	0.99
FYN	cg20706496	0.93
FYN	cg21021905	0.91
FYN	cg25189764	0.91
OSBPL8	cg24739189	0.83
PI3	cg24476939	0.93
PILRA	cg20784591	0.75
POLB	cg07069743	0.49
POLB	cg18894794	0.63
RCBTB2	cg00750684	0.54
RNF19B	cg10014674	0.55
SRPK2	cg13660622	0.74
SRPK2	cg15857470	0.93
TRIM33	cg18199720	0.66

ISSN: 1479-5876