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Table 1 Inventory of NYU bio-samples from WTC dust-exposed/control SHR rats

From: Complementary biobank of rodent tissue samples to study the effect of World Trade Center exposure on cancer development

Harvest time post-exposure Exposure type Number of rats with organs and blood storeda
Day 1 Naïve 6
ISO control 5
26.5–35.5b mg dust/m3 6
Day 30 Naïve 6
ISO control 6
26.6–32.0 mg dust/m3 6
Day 60 Naïve 6
ISO control 6
32.7–35.5 mg dust/m3 6
Day 120 Naïve 6
ISO control 6
32.7–35.5 mg dust/m3 6
Day 240 Naïve 12
ISO control 6
32.0–35.5 mg dust/m3 5
Day 360 Naïve 6
ISO control 6
26.6–42.8 mg dust/m3 17
Total   123
  1. Tissues from the male F344 rats of the earlier intratracheal inhalation WTC dust-exposure studies (also 2 h/day on 2 consecutive days) are also available in the Biobank, although the group sizes are not presented here
  2. a All rats were males. Organs isolated for each rat included the heart, aortic arches, prostate, kidney, liver, thyroid, spleen; these materials were frozen and/or stored in formalin. TA leg muscle, plasma, serum, bone marrow and lung lavage fluid (supernatant) were only frozen. Some lungs were lavaged and then frozen; others were inflated and then fixed
  3. b Values shown cover range of dust levels presented to the rats over the course of their respective two exposures. Target value each day was ≈ 33–35 mg/m3. To avoid bias, rats from any given exposure set were randomly allocated into the various post-exposure time groups; this explains commonality among ranges indicated