Fig. 7
Tumourigenesis and CCNB1, E-cadherin and N-cadherin expression in vivo. a Representative images of tumours in the nude mouse GH3 xenograft model. b Statistical analysis of xenograft tumour volume. c Statistical analysis of xenograft tumour weight. d Representative immunohistochemistry images of xenograft tumour tissues with CCNB1, E-cadherin and N-cadherin staining (×400). e The percentage of cells that stained positive was quantified using Image Pro Plus software according to the IOD to Area ratio at ×400 magnification. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001 (Con scramble-shRNA-transfected GH3 cell group, shRNA CCNB1 shRNA-transfected GH3 cell group)