miRNA
|
Breast cancer
|
Benign tissue
|
logFC
|
p*
|
---|
Mean ± SD
|
Mean ± SD
|
---|
let-7b-5p
|
3.41 ± 1.11
|
4.28 ± 1.05
|
− 0.87
|
0.0094
|
let-7c
|
2.54 ± 0.99
|
3.84 ± 0.90
|
− 1.30
|
4.76E−5
|
miR-126-3p
|
2.98 ± 1.04
|
4.24 ± 0.79
|
− 1.26
|
5.42E−5
|
miR-126-5p
|
− 2.05 ± 1.00
|
− 0.86 ± 0.80
|
− 1.18
|
6.19E−5
|
miR-143-3p
|
2.84 ± 1.16
|
4.18 ± 0.81
|
− 1.35
|
6.19E−5
|
miR-145-5p
|
3.31 ± 1.53
|
5.98 ± 0.69
|
− 2.67
|
1.79E−8
|
miR-155-5p
|
− 0.54 ± 1.37
|
− 2.23 ± 1.11
|
1.69
|
5.04E−5
|
miR-146a-5p
|
− 0.48 ± 1.36
|
− 1.22 ± 1.08
|
0.74
|
0.048
|
miR-3182
|
− 7.24 ± 1.71
|
− 9.17 ± 1.43
|
1.93
|
0.028
|
miR-17-5p
|
− 4.70 ± 1.45
|
− 4.92 ± 1.11
|
0.22
|
0.60
|
miR-20a-5p
|
2.36 ± 1.18
|
2.29 ± 0.67
|
0.069
|
0.81
|
miR-92a-3p
|
1.96 ± 1.03
|
2.60 ± 0.76
|
− 0.65
|
0.025
|
miR-106b-5p
|
0.45 ± 1.03
|
− 0.84 ± 0.61
|
1.29
|
3.81E−5
|
miR-93-5p
|
1.76 ± 1.03
|
0.75 ± 0.56
|
1.01
|
0.00031
|
- Expression levels are presented as mean (standard deviation) of normalized PCR quantification cycle (Cq) values based on the average of the normalizer assay detected in all samples and the formula: normalized Cq = average Cq (all samples) − assay Cq (sample). Negative PCR expression values indicate lower expression levels compared to the normalizer
- * False discovery rate (FDR) adjusted p-value. E indicates exponential number