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Table 2 The most up- and downregulated miRNAs in cancer compared to benign tissue, sorted by logFC

From: Differential expression of the miR-17-92 cluster and miR-17 family in breast cancer according to tumor type; results from the Norwegian Women and Cancer (NOWAC) study

MiRNA

LogFC cancer versus benign

p*

miR-2964a-5p

4.859

6.74E−44

miR-4419b

1.249

1.84E−23

miR-3164

1.146

2.22E−12

miR-K12-5-5p

1.143

2.90E−12

miR-221-5p

0.924

1.51E−17

miR-585

0.920

1.80E−11

miR-342-3p

0.865

1.07E−07

miR-766-5p

0.846

1.77E−10

miR-4478

0.828

1.03E−21

miR-338-5p

0.815

2.64E−12

miR-21-5p

0.703

8.74E−04

miR-342-5p

0.667

3.27E−13

miR-149-3p

0.660

1.46E−08

miR-5196-3p

0.650

6.37E−20

miR-182-5p

0.644

9.59E−08

miR-4644

0.592

8.30E−08

miR-224-3p

0.588

2.81E−11

miR-4768-5p

0.586

2.13E−12

miR-4778-3p

0.565

5.08E−17

miR-4417

0.559

5.72E−05

miR-451a

− 2.647

1.89E−18

miR-143-3p

− 2.096

4.90E−27

miR-99a-5p

− 2.093

3.52E−24

miR-4328

− 2.090

1.42E−27

miR-145-5p

− 2.061

3.39E−29

miR-205-5p

− 2.027

1.45E−12

miR-195-5p

− 2.023

8.11E−25

miR-125b-5p

− 1.970

8.70E−14

miR-126-3p

− 1.862

1.89E−25

miR-26b-5p

− 1.837

1.01E−24

miR-4324

− 1.651

1.04E−25

miR-29a-3p

− 1.592

3.44E−12

miR-10b-5p

− 1.483

6.87E−24

miR-30b-5p

− 1.452

1.03E−15

let-7d-5p

− 1.450

6.25E−21

miR-130a-3p

− 1.406

4.80E−19

miR-199b-5p

− 1.400

1.84E−23

miR-29b-3p

− 1.339

1.56E−14

miR-199a-3p

− 1.316

2.13E−13

miR-24-3p

− 1.287

7.37E−18

  1. Log fold change (logFC) values are calculated, based on the log2 transformed intensity values (Hy3) by microarray analyses, comparing breast cancer to benign tissue controls. The 20 most upregulated and the 20 most downregulated miRNAs, sorted by highest and lowest logFC, respectively, are presented
  2. * False discovery rate (FDR) adjusted p-value. E indicates exponential number
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Journal of Translational Medicine

ISSN: 1479-5876

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