Table 1 Demographic data of patients and controls at admission
Parameters | Acute SCI (n = 44) | Controls (n = 66) | p value |
|---|---|---|---|
Age (year), median (IQR) | 49.5 (35.5, 58.8) | 41.0 (35.8, 46.3) | .084 |
Male | 36 | 38 | .012 |
Body mass index | 24.5 (21.0, 28.2) | 24.3 (20.3, 25.5) | .469 |
Level of SCI | |||
 C1–C4 | 28 | NA |  |
 Below C4 | 16 | NA |  |
Injury Severity Score at admission | |||
 Total, median (IQR) | 17.5 (16, 25.5) | NA |  |
 AIS-head/neck, median (IQR) | 4 (4, 4) | NA |  |
 AIS-thorax, median (IQR) | 0 (0, 0) | NA |  |
 AIS-abdomen, median (IQR) | 0 (0, 0) | NA |  |
 AIS-extremities, median (IQR) | 0 (0, 1.75) | NA |  |
JOA score at admission, median (IQR) | 4 (3, 7.5) | NA | Â |
Neurosurgical intervention (n = 39) | |||
 Emergent surgery | 23 | NA |  |
 Elective surgery | 28 | NA |  |
Laboratory data at presentation, median (IQR) | |||
 WBC (× 103/ml) | 11.3 (7.67, 15.1) | 5.6 (4.92, 7.6) | ≤ 0.001 |
 Platelet counts (× 103/ml) | 222 (182, 259) | 227 (194, 298) | .238 |
Plasma DNA at presentation, median (IQR) | |||
 Plasma nuclear DNA (ng/ml) | 40.3 (23.2, 96.5) | 25.1 (19.45, 38.07) | .005 |
 Plasma mitochondrial DNA (ng/ml) | 43.6 (20.8, 99.7) | 12.6 (8.25, 17.02) | ≤ 0.001 |