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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: 90-gene signature assay for tissue origin diagnosis of brain metastases

Fig. 2

a Threshold identification for discrimination of PBTs and BMs. The grey spots indicate specimens corrected classified by 90-gene expression signature, whereas red spots show specimens with discordant results comparing with reference diagnosis. The similarity score of 70 (solid line) was identified as threshold by the Optimal Binning algorithm to discriminate PBTs and BMs. b Boxplot comparing the distribution of similarity scores of PBTs and BMs misclassified as brain tumors by 90-gene expression signature. The grey spots indicate the highest similarity scores of each specimens. The boxplots show the distribution of the highest similarity scores of PBTs (red) and misclassified BMs (cyan)

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