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Table 3 Ranges of the personalization parameters for identifying the patient-specific model parameters

From: Predicting response to pembrolizumab in metastatic melanoma by a new personalization algorithm

Model parameter Definition Personalization parameter range Units
\(a_{pem}\) Maximum effect of pembrolizumab on activation of CD8+ T cells \(10\) to \(10^{4}\)
\(\gamma_{mel}\) Tumor growth rate \(3.269 \times 10^{ - 3}\) or \(5 \times 10^{ - 3}\) Day−1