Table 3 Ranges of the personalization parameters for identifying the patient-specific model parameters
From: Predicting response to pembrolizumab in metastatic melanoma by a new personalization algorithm
Model parameter | Definition | Personalization parameter range | Units |
|---|---|---|---|
\(a_{pem}\) | Maximum effect of pembrolizumab on activation of CD8+ T cells | \(10\) to \(10^{4}\) | – |
\(\gamma_{mel}\) | Tumor growth rate | \(3.269 \times 10^{ - 3}\) or \(5 \times 10^{ - 3}\) | Day−1 |