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Table 3 Correlations between gene expression of cytokines and inflammation/oxidation-related molecules

From: Plasma peroxiredoxin changes and inflammatory cytokines support the involvement of neuro-inflammation and oxidative stress in Autism Spectrum Disorder

Cytokine or inflammation-related molecules AHR HSP70i IL6 IL10 IL12A IL1 beta COX1 COX2 PRX2 PRX5 STAT3 TNF-alpha
AHR     p = 0.0014
r = 0.75
pFDR = 0.031
  p = 0.0265
r = 0.56
pFDR = 0.159
  p = 0.0458
r = 0.51
pFDR = 0.178
  p = 0.0281
r = − 0.55
pFDR = 0.154
p = 0.0027
r = 0.70
pFDR = 0.036
p = 0.0417
r = 0.51
pFDR = 0.183
HSP70i    p = 0.0176
r = − 0.58
pFDR = 0.129
  p = 0.0161
r = − 0.59
pFDR = 0.132
       
IL6      p = 0.0079
r = 0.64
pFDR = 0.075
       
IL10 p = 0.0112
r = 0.44
pFDR = 0.082
  p = 0.0484
r = 0.35
pFDR = 0.213
   p = 0.0012
r = 0.73
pFDR = 0.040
      p = 0.0010
r = 0.74
pFDR = 0.066
IL12A   p = 0.0346
r = − 0,37
pFDR = 0.19
p < 0.0001
r = 0.63
pFDR = 0.003
p = 0.0049
r = 0.48
pFDR = 0.064
  p = 0.0059
r = 0.65
pFDR = 0.065
      
IL1 beta   p = 0.006
r = − 0.47
pFDR = 0.057
p = 0.0053
r = 0.47
pFDR = 0.058
         p = 0.0015
r = 0.73
pFDR = 0.025
COX1            p = 0.0420
r = 0.65
pFDR = 0.173
 
COX2           p = 0.0320
r = − 0.69
pFDR = 0.162
  
PRX2             
PRX5   p = 0.0368
r = − 0.36
pFDR = 0.187
      p = 0.0014
r = − 0.53
pFDR = 0.023
   p = 0.0386
r = − 0.52
pFDR = 0.182
 
STAT3 p < 0.0001
r = 0.69
pFDR = 0.007
   p = 0.0176
r = 0.41
pFDR = 0.116
    p = 0.0484
r = 0.35
pFDR = 0.213
  p = 0.0221
r = − 0.40
pFDR = 0.133
  p = 0.0196
r = 0.58
pFDR = 0.129
TNF-alpha p = 0.0194
r = 0.40
pFDR = 0.128
p = 0.0435
r = − 0.35
pFDR = 0.205
  p = 0.0002
r = 0.60
pFDR = 0.004
       p = 0.0092
r = 0.45
pFDR = 0.076
 
  1. Significant correlations (p ≤ 0.05) are shown. Correlations found in ASD children alone are shown in underline; correlations found in the whole population (ASD and TD children) are shown in italic