|
Variable
|
Non-ARDS (n = 160)
|
ARDS (n = 76)
|
P value
|
|---|
|
Age (year)
|
63.89 ± 18.00
|
68.07 ± 17.86
|
0.096
|
|
Sex (male)
|
108 (67.5%)
|
59 (77.6%)
|
0.127
|
|
Bacteraemia
|
2 (1.25%)
|
2 (2.63%)
|
0.596
|
|
Sepsis
|
127 (79.4%)
|
64 (84.2%)
|
0.479
|
|
Septic shock
|
55 (34.4%)
|
30 (39.5%)
|
0.470
|
|
Pneumonia
|
84 (52.5%)
|
43 (56.6%)
|
0.579
|
|
Vasopressora
|
69 (43.1%)
|
35 (46.1%)
|
0.677
|
|
Fracture
|
3 (1.88%)
|
1 (1.32%)
|
1.000
|
|
Pulmonary contusion
|
0 (0%)
|
3 (3.95%)
|
0.033*
|
|
Aspiration
|
5 (3.13%)
|
5 (6.58%)
|
0.299
|
|
Multiple transfusion
|
15 (9.38%)
|
9 (11.84%)
|
0.646
|
|
Previous ARDS
|
0 (0%)
|
2 (2.63%)
|
0.103
|
|
Autoimmune disease
|
0 (0%)
|
0 (0%)
|
–
|
|
Diabetes
|
30 (18.75%)
|
12 (15.79%)
|
0.716
|
|
Previous sepsis
|
0 (0%)
|
1 (1.32%)
|
0.322
|
|
Tobacco
|
53 (33.13%)
|
32 (42.11%)
|
0.194
|
|
Familial diabetes mellitus
|
13 (8.13%)
|
3 (3.95%)
|
0.280
|
|
Leukaemia
|
0 (0%)
|
1 (1.32%)
|
0.322
|
|
Dialysis
|
3 (1.88%)
|
2 (2.63%)
|
0.658
|
|
Metastatic solid tumour
|
8 (5%)
|
2 (2.63%)
|
0.507
|
|
Immunosuppression
|
1 (0.63%)
|
0 (0%)
|
1.000
|
|
Hepatic encephalopathy
|
1 (0.63%)
|
0 (0%)
|
1.000
|
|
Hepatocirrhosis
|
2 (1.25%)
|
0 (0%)
|
1.000
|
|
Alcohol abuse for 12 months
|
18 (11.25%)
|
7 (9.21%)
|
0.821
|
|
APACHE II score
|
19.98 ± 5.77
|
19.92 ± 5.94
|
0.947
|
|
PH
|
7.38 ± 0.09
|
7.37 ± 0.11
|
0.509
|
|
Minimum systolic pressure
|
102.45 ± 20.62
|
92.97 ± 18.70
|
0.001*
|
|
Maximum systolic pressure
|
140.76 ± 23.17
|
138.20 ± 26.63
|
0.450
|
|
Minimum MAP
|
78.25 ± 72.22
|
69.20 ± 14.88
|
0.281
|
|
Maximum MAP
|
98.21 ± 16.92
|
97.53 ± 17.76
|
0.777
|
|
Minimum heart rate
|
91.41 ± 16.80
|
87.04 ± 18.85
|
0.074
|
|
Maximum heart rate
|
122.19 ± 20.30
|
122.62 ± 23.18
|
0.886
|
|
Minimum respiratory rate
|
22.22 ± 4.65
|
25.08 ± 4.40
|
0.000*
|
|
Maximum respiratory rate
|
31.08 ± 5.70
|
34.50 ± 6.23
|
0.000*
|
|
Minimum temperature
|
36.73 ± 0.92
|
36.63 ± 0.79
|
0.412
|
|
Minimum creatinine
|
1.44 ± 1.43
|
1.36 ± 0.98
|
0.655
|
|
Maximum creatinine
|
1.56 ± 1.49
|
1.50 ± 1.07
|
0.754
|
|
Minimum glucose
|
140.32 ± 104.32
|
123.79 ± 58.33
|
0.199
|
|
Minimum haematocrit
|
30.13 ± 6.37
|
29.13 ± 7.10
|
0.282
|
|
Minimum white blood cell count
|
11.55 ± 5.72
|
12.63 ± 7.20
|
0.253
|
|
Minimum sodium
|
140.67 ± 6.34
|
138.80 ± 6.25
|
0.034*
|
|
Minimum potassium
|
3.97 ± 0.68
|
3.89 ± 0.55
|
0.366
|
- The binary variables are described as counts and percentages and were evaluated by the Chi-squared test or Fisher’s exact test. Continuous variables of each group are presented as the mean ± SEM. Student’s t-test was used to compare the normally distributed continuous variables
- ARDS acute respiratory distress syndrome, MAP mean arterial pressure, APACHE II Acute Physiology and Chronic Health Evaluation II
- *P < 0.05, ARDS compared with non-ARDS
- aVasopressor use before and 24 h after entering the ICU
