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Table 1 Baseline characteristics and clinical and laboratory parameters in the training dataset

From: Predictive model for acute respiratory distress syndrome events in ICU patients in China using machine learning algorithms: a secondary analysis of a cohort study

Variable

Non-ARDS (n = 160)

ARDS (n = 76)

P value

Age (year)

63.89 ± 18.00

68.07 ± 17.86

0.096

Sex (male)

108 (67.5%)

59 (77.6%)

0.127

Bacteraemia

2 (1.25%)

2 (2.63%)

0.596

Sepsis

127 (79.4%)

64 (84.2%)

0.479

Septic shock

55 (34.4%)

30 (39.5%)

0.470

Pneumonia

84 (52.5%)

43 (56.6%)

0.579

Vasopressora

69 (43.1%)

35 (46.1%)

0.677

Fracture

3 (1.88%)

1 (1.32%)

1.000

Pulmonary contusion

0 (0%)

3 (3.95%)

0.033*

Aspiration

5 (3.13%)

5 (6.58%)

0.299

Multiple transfusion

15 (9.38%)

9 (11.84%)

0.646

Previous ARDS

0 (0%)

2 (2.63%)

0.103

Autoimmune disease

0 (0%)

0 (0%)

–

Diabetes

30 (18.75%)

12 (15.79%)

0.716

Previous sepsis

0 (0%)

1 (1.32%)

0.322

Tobacco

53 (33.13%)

32 (42.11%)

0.194

Familial diabetes mellitus

13 (8.13%)

3 (3.95%)

0.280

Leukaemia

0 (0%)

1 (1.32%)

0.322

Dialysis

3 (1.88%)

2 (2.63%)

0.658

Metastatic solid tumour

8 (5%)

2 (2.63%)

0.507

Immunosuppression

1 (0.63%)

0 (0%)

1.000

Hepatic encephalopathy

1 (0.63%)

0 (0%)

1.000

Hepatocirrhosis

2 (1.25%)

0 (0%)

1.000

Alcohol abuse for 12 months

18 (11.25%)

7 (9.21%)

0.821

APACHE II score

19.98 ± 5.77

19.92 ± 5.94

0.947

PH

7.38 ± 0.09

7.37 ± 0.11

0.509

Minimum systolic pressure

102.45 ± 20.62

92.97 ± 18.70

0.001*

Maximum systolic pressure

140.76 ± 23.17

138.20 ± 26.63

0.450

Minimum MAP

78.25 ± 72.22

69.20 ± 14.88

0.281

Maximum MAP

98.21 ± 16.92

97.53 ± 17.76

0.777

Minimum heart rate

91.41 ± 16.80

87.04 ± 18.85

0.074

Maximum heart rate

122.19 ± 20.30

122.62 ± 23.18

0.886

Minimum respiratory rate

22.22 ± 4.65

25.08 ± 4.40

0.000*

Maximum respiratory rate

31.08 ± 5.70

34.50 ± 6.23

0.000*

Minimum temperature

36.73 ± 0.92

36.63 ± 0.79

0.412

Minimum creatinine

1.44 ± 1.43

1.36 ± 0.98

0.655

Maximum creatinine

1.56 ± 1.49

1.50 ± 1.07

0.754

Minimum glucose

140.32 ± 104.32

123.79 ± 58.33

0.199

Minimum haematocrit

30.13 ± 6.37

29.13 ± 7.10

0.282

Minimum white blood cell count

11.55 ± 5.72

12.63 ± 7.20

0.253

Minimum sodium

140.67 ± 6.34

138.80 ± 6.25

0.034*

Minimum potassium

3.97 ± 0.68

3.89 ± 0.55

0.366

  1. The binary variables are described as counts and percentages and were evaluated by the Chi-squared test or Fisher’s exact test. Continuous variables of each group are presented as the mean ± SEM. Student’s t-test was used to compare the normally distributed continuous variables
  2. ARDS acute respiratory distress syndrome, MAP mean arterial pressure, APACHE II Acute Physiology and Chronic Health Evaluation II
  3. *P < 0.05, ARDS compared with non-ARDS
  4. aVasopressor use before and 24 h after entering the ICU
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Journal of Translational Medicine

ISSN: 1479-5876

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