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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Photopheresis efficacy in the treatment of rheumatoid arthritis: a pre-clinical proof of concept

Fig. 3

ECP treatment modifies Th17 frequency. Immune cell profile was analyzed in mice treated or not by ECP 12 days after beginning of the treatment. a Representative flow cytometry profile of regulatory T cells (FoxP3+/CD25+) and Th1 (IFNγ+) and Th17 (IL17+) cells labeling, on gated CD3 + CD4 + T lymphocytes. b Mean percentages (± standard deviation) of Treg, Th1, and Th17 in the blood of treated and non-treated mice (10 mice per groups in two independent experiments). c Cytokine concentrations in sera were measured by cytometric bead array. Bars represent the mean and standard deviation for 10 mice per groups in two independent experiments. Statistical differences between treated and untreated mice were determined by Mann and Whitney test

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