Fig. 5

High ERs, EGFR and Notch1 expression correlated with poor prognosis of advanced NSCLC. a Representative examples of IHC expression of ERα, ERβ, EGFR and Notch1 in NSCLC tumor tissues (Tumor) and the paired non-tumor adjacent tissues (NAT). Original magnification: ×200 for all samples. b Unpaired t test of ERα, ERβ, EGFR and Notch1 between Tumor group (N = 93) and NAT group (N = 87). IHC score was an index of ERα, ERβ, EGFR and Notch1 expression levels. c Kaplan–Meier curves showing overall survival of the late-stage NSCLC patients for ERα, ERβ and EGFR expression, respectively. d Overall survival of the late-stage NSCLC patients with grouped high-expression receptors. e Overall survival of the late-stage NSCLC patients with at least two high-expression receptors for Notch1 expression. p values were calculated using the log-rank test