Anthropometric parameters
|
Age (years)
|
62.82 ± 6.8
|
64.55 ± 5.82
|
0.320
|
BMI (kg/m2)
|
28.23 ± 4.05
|
27.94 ± 3.54
|
0.665
|
Prostatic volume (cc)
|
45.71 ± 25.96
|
43.5 ± 19.52
|
0.716
|
Glycemic profile
|
Glucose (mmol/L)
|
5.90 ± 1.23
|
6.65 ± 2.35
|
0.050
|
Insulin (pmol/L)
|
95.42 ± 60.84
|
89.73 ± 48.41
|
0.847
|
HOMA-IR
|
3.75 ± 2.92
|
3.92 ± 2.76
|
0.795
|
HbA1c (%)
|
5.77 ± 0.67
|
6.01 ± 0.86
|
0.152
|
Lipid profile
|
Cholesterol (mmol/L)
|
5.02 ± 1.06
|
4.93 ± 1.01
|
0.609
|
HDL cholesterol (mmol/L)
|
1.49 ± 0.71
|
1.35 ± 0.39
|
0.484
|
LDL cholesterol (mmol/L)
|
3.23 ± 1.29
|
2.84 ± 0.88
|
0.148
|
Triglycerides (mmol/L)
|
1.40 ± 0.74
|
1.63 ± 0.99
|
0.526
|
Hepatic profile
|
AST (µkat/L)
|
0.38 ± 0.19
|
0.32 ± 0.07
|
0.104
|
ALT (µkat/L)
|
0.40 ± 0.21
|
0.36 ± 0.11
|
0.816
|
GGT (µkat/L)
|
0.72 ± 0.88
|
0.68 ± 0.50
|
0.783
|
Renal profile
|
Uric acid (µmol/L)
|
373.57 ± 88.63
|
463.39 ± 559.75
|
0.595
|
Urea (mmol/L)
|
13.99 ± 3.34
|
14.44 ± 5.40
|
0.922
|
Creatinine (μmol/L)
|
83.98 ± 1.77
|
77.79 ± 2.19
|
0.187
|
Hormonal profile
|
SHBG (nmol/L)
|
46.64 ± 50.65
|
38.93 ± 16.71
|
0.756
|
Testosterone (nmol/L)
|
14.22 ± 4.62
|
12.88 ± 5.80
|
0.158
|
Tumoral markers
|
Total PSA (μg/L)
|
7.64 ± 4.42
|
13.14 ± 11.47
|
0.003
|
Biofluid biomarker profile
|
Semen cytokines (pg/mg of total protein)
|
sTWEAK
|
989.07 ± 624.08
|
550.54 ± 380.25
|
0.003
|
sCD163
|
1449.03 ± 2060.7
|
1392.09 ± 1265.89
|
0.391
|
sFn14
|
645.31 ± 434.45
|
609.99 ± 413.28
|
0.781
|
sCXCL5
|
360.23 ± 376.07
|
212.72 ± 240.72
|
0.179
|
sCCL7
|
3.09 ± 3.34
|
3 ± 2.69
|
0.767
|
Serum cytokines (pg/mL)
|
sTWEAK
|
1118.74 ± 344.32
|
1331.08 ± 830.51
|
0.225
|
sCD163
|
346.68 ± 286.15
|
349.46 ± 276.29
|
0.976
|
sCXCL5
|
1234.89 ± 630.15
|
1346.42 ± 703.23
|
0.439
|
sCCL7
|
2.6 ± 17.62
|
23.49 ± 107.42
|
0.508
|
Urine cytokines (pg/mg of creatinine)
|
sTWEAK
|
199.62 ± 257.43
|
128.24 ± 151.58
|
0.723
|
sCD163
|
166.07 ± 804.1
|
1173.09 ± 3368.52
|
0.401
|
sFn14
|
182.5 ± 287.53
|
159.69 ± 236.24
|
0.479
|
sCXCL5
|
132.97 ± 142.43
|
161.98 ± 165.27
|
0.423
|
Semen cell sediment gene expression (arbitrary units, 2−∆∆Ct)
|
KLK2
|
1.12 ± 0.41
|
0.82 ± 0.45
|
0.050
|
KLK3
|
1.16 ± 0.75
|
1.02 ± 0.74
|
0.529
|
CXCR2
|
2.68 ± 3.6
|
4.03 ± 3.7
|
0.089
|
CCR3
|
2.53 ± 3.23
|
6.31 ± 8.1
|
0.069
|
CD163
|
6.37 ± 6.57
|
5.68 ± 5.54
|
0.796
|
Fn14
|
4.15 ± 2.82
|
8.52 ± 7.69
|
0.077
|