Table 2 Multivariable analysis
Variable | PFS as the dependent variable | OS as the dependent variable | ||||||
|---|---|---|---|---|---|---|---|---|
Univariate | Multivariable | Univariate | Multivariable | |||||
HR (95% CI) | p-value | HR (95% CI) | p-value | HR (95% CI) | p-value | HR (95% CI) | p-value | |
Baseline LDH | 2.79 (1.55–5.03) | < 0.001 | 3.37 (1.65–6.89) | < 0.001 | ||||
Baseline CRP | 2.38 (1.28–4.42) | 0.006 | 2.16 (1.15–4.07) | 0.017 | 2.43 (1.17–5.06) | 0.017 | ||
ECOG | 2.87 (1.20–6.90) | 0.018 | 2.67 (1.04–6.84) | 0.04 | 4.02 (1.65–9.79) | 0.002 | ||
Number of metastatic sites | 2.33 (1.28–4.26) | 0.006 | 3.06 (1.44–6.52) | 0.004 | 2.38 (1.10–5.14) | 0.027 | ||
Undetectable ctDNA | 0.18 (0.09–0.35) | < 0.001 | 0.20 (0.10–0.40) | < 0.001 | 0.13 (0.06–0.29) | < 0.001 | 0.16 (0.07–0.36) | < 0.001 |