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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: TREM2 regulates obesity-induced insulin resistance via adipose tissue remodeling in mice of high-fat feeding

Fig. 6

TREM2−/− mice demonstrated more severe hepatic steatosis under HFD feeding. WT and TREM2−/− mice of C57BL/6 of 6 weeks were fed with HFD for 12 weeks. a Liver mass and b proportion of bodyweight of WT and TREM2−/− mice after 12 weeks of HFD (N = 10/group) feeding. c Representative images of H&E staining of liver of WT and TREM2−/− mice after 12 weeks of HFD feeding. Original magnification is ×100 and ×400 (within box at bottom right), scale bar = 200 μm. Data are presented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

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