Table 4 Consistency in BRAF and NRAS pathogenic/likely pathogenic variants in our cohort
| Â | Cases with a mutation in the primary tumor | Consistent mutation pattern with metastasis (%) |
|---|---|---|
BRAF mutations | ||
 Primary vs. lymph node metastasis | 18 | 17 (94.4) |
 Primary vs. visceral metastasis | 3 | 3 (100) |
 Primary vs. metastasis | 21 | 20 (95.2) |
 Discovery cohort | 17 | 17 (100) |
 Validation cohort | 4 | 3 (75) |
NRAS mutations | ||
 Primary vs. lymph node metastasis | 3 | 3 (100) |
 Primary vs. visceral metastasis | 4 | 3 (75) |
 Primary vs. metastasis | 7 | 6 (85.7) |
 Discovery cohort | 5 | 4 (80) |
 Validation cohort | 2 | 2 (100) |