TY - JOUR AU - Cossu, A. AU - Casula, M. AU - Cesaraccio, R. AU - Lissia, A. AU - Colombino, M. AU - Sini, M. C. PY - 2017 DA - 2017// TI - Epidemiology and genetic susceptibility of malignant melanoma in North Sardinia, Italy JO - Eur J Cancer Prev. VL - 26 UR - https://doi.org/10.1097/CEJ.0000000000000223 DO - 10.1097/CEJ.0000000000000223 ID - Cossu2017 ER - TY - STD TI - SEER Cancer statistics review 1975-2015. https://seer.cancer.gov/csr/1975_2015/results_merged/sect_16_melanoma_skin.pdf. Accessed 01 May 2019. UR - https://seer.cancer.gov/csr/1975_2015/results_merged/sect_16_melanoma_skin.pdf ID - ref2 ER - TY - CHAP AU - Hung, C. Y. AU - Chang, J. W. C. ED - Riker, A. PY - 2018 DA - 2018// TI - Chemotherapy and biochemotherapy for melanoma BT - Melanoma. A modern multidisciplinary approach PB - Springer International Publishing AG CY - Basel ID - Hung2018 ER - TY - JOUR AU - Schadendorf, D. AU - Akkooi, A. C. J. AU - Berking, C. AU - Griewank, K. G. AU - Gutzmer, R. AU - Hauschild, A. PY - 2018 DA - 2018// TI - Melanoma JO - Lancet VL - 392 UR - https://doi.org/10.1016/S0140-6736(18)31559-9 DO - 10.1016/S0140-6736(18)31559-9 ID - Schadendorf2018 ER - TY - JOUR AU - Gos, A. AU - Jurkowska, M. AU - Akkooi, A. AU - Robert, C. AU - Kosela-Paterczyk, H. AU - Koljenović, S. PY - 2014 DA - 2014// TI - Molecular characterization and patient outcome of melanoma nodal metastases and an unknown primary site JO - Ann Surg Oncol VL - 21 UR - https://doi.org/10.1245/s10434-014-3799-y DO - 10.1245/s10434-014-3799-y ID - Gos2014 ER - TY - JOUR AU - Colombino, M. AU - Capone, M. AU - Lissia, A. AU - Cossu, A. AU - Rubino, C. AU - Giorgi, V. PY - 2012 DA - 2012// TI - BRAF/NRAS mutation frequencies among primary tumors and metastases in patients with melanoma JO - J Clin Oncol VL - 30 UR - https://doi.org/10.1200/JCO.2011.41.2452 DO - 10.1200/JCO.2011.41.2452 ID - Colombino2012 ER - TY - JOUR AU - Riveiro-Falkenbach, E. AU - Villanueva, C. A. AU - Garrido, M. C. AU - Ruano, Y. AU - Garcia-Martin, R. M. AU - Godoy, E. PY - 2015 DA - 2015// TI - Intra- and inter-tumoral homogeneity of BRAF(V600E) mutations in melanoma tumors JO - J Investig Dermatol. VL - 135 UR - https://doi.org/10.1038/jid.2015.229 DO - 10.1038/jid.2015.229 ID - Riveiro-Falkenbach2015 ER - TY - JOUR AU - Saroufim, M. AU - Habib, R. H. AU - Gerges, R. AU - Saab, J. AU - Loya, A. AU - Amr, S. S. PY - 2014 DA - 2014// TI - Comparing BRAF mutation status in matched primary and metastatic cutaneous melanomas: implications on optimized targeted therapy JO - Exp Mol Pathol. VL - 97 UR - https://doi.org/10.1016/j.yexmp.2014.09.008 DO - 10.1016/j.yexmp.2014.09.008 ID - Saroufim2014 ER - TY - JOUR AU - Omholt, K. AU - Platz, A. AU - Kanter, L. AU - Ringborg, U. AU - Hansson, J. PY - 2003 DA - 2003// TI - NRAS, and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression JO - Clin Cancer Res VL - 9 ID - Omholt2003 ER - TY - JOUR AU - Lin, J. AU - Goto, Y. AU - Murata, H. AU - Sakaizawa, K. AU - Uchiyama, A. AU - Saida, T. PY - 2011 DA - 2011// TI - Polyclonality of BRAF mutations in primary melanoma and the selection of mutant alleles during progression JO - Br J Cancer VL - 104 UR - https://doi.org/10.1038/sj.bjc.6606072 DO - 10.1038/sj.bjc.6606072 ID - Lin2011 ER - TY - JOUR AU - Sini, M. C. AU - Doneddu, V. AU - Paliogiannis, P. AU - Casula, M. AU - Colombino, M. AU - Manca, A. PY - 2018 DA - 2018// TI - Genetic alterations in main candidate genes during melanoma progression JO - Oncotarget. VL - 9 UR - https://doi.org/10.18632/oncotarget.23989 DO - 10.18632/oncotarget.23989 ID - Sini2018 ER - TY - JOUR AU - Palmieri, G. AU - Colombino, M. AU - Casula, M. AU - Manca, A. AU - Mandalà, M. AU - Cossu, A. PY - 2018 DA - 2018// TI - Molecular pathways in melanomagenesis: what we learned from next-generation sequencing approaches JO - Curr Oncol Rep. VL - 20 UR - https://doi.org/10.1007/s11912-018-0733-7 DO - 10.1007/s11912-018-0733-7 ID - Palmieri2018 ER - TY - JOUR PY - 2015 DA - 2015// TI - Genomic classification of cutaneous melanoma JO - Cell VL - 161 UR - https://doi.org/10.1016/j.cell.2015.05.044 DO - 10.1016/j.cell.2015.05.044 ID - ref13 ER - TY - JOUR AU - Hayward, N. K. AU - Wilmott, J. S. AU - Waddell, N. AU - Johansson, P. A. AU - Field, M. A. AU - Nones, K. PY - 2017 DA - 2017// TI - Whole-genome landscapes of major melanoma subtypes JO - Nature VL - 545 UR - https://doi.org/10.1038/nature22071 DO - 10.1038/nature22071 ID - Hayward2017 ER - TY - JOUR AU - Krauthammer, M. AU - Kong, Y. AU - Ha, B. H. AU - Evans, P. AU - Bacchiocchi, A. AU - McCusker, J. P. PY - 2012 DA - 2012// TI - Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma JO - Nat Genet VL - 44 UR - https://doi.org/10.1038/ng.2359 DO - 10.1038/ng.2359 ID - Krauthammer2012 ER - TY - JOUR AU - Hodis, E. AU - Watson, I. R. AU - Kryukov, G. V. AU - Arold, S. T. AU - Imielinski, M. AU - Theurillat, J. P. PY - 2012 DA - 2012// TI - A landscape of driver mutations in melanoma JO - Cell VL - 150 UR - https://doi.org/10.1016/j.cell.2012.06.024 DO - 10.1016/j.cell.2012.06.024 ID - Hodis2012 ER - TY - JOUR AU - Berger, M. F. AU - Hodis, E. AU - Heffernan, T. P. AU - Deribe, Y. L. AU - Lawrence, M. S. AU - Protopopov, A. PY - 2012 DA - 2012// TI - Melanoma genome sequencing reveals frequent PREX2 mutations JO - Nature VL - 485 UR - https://doi.org/10.1038/nature11071 DO - 10.1038/nature11071 ID - Berger2012 ER - TY - JOUR AU - Palmieri, G. AU - Ombra, M. AU - Colombino, M. AU - Casula, M. AU - Sini, M. AU - Manca, A. PY - 2015 DA - 2015// TI - Multiple molecular pathways in melanomagenesis: characterization of therapeutic targets JO - Front Oncol. VL - 5 UR - https://doi.org/10.3389/fonc.2015.00183 DO - 10.3389/fonc.2015.00183 ID - Palmieri2015 ER - TY - JOUR AU - Grzywa, T. M. AU - Paskal, W. AU - Włodarski, P. K. PY - 2017 DA - 2017// TI - Intratumor and intertumor heterogeneity in melanoma JO - Transl Oncol. VL - 10 UR - https://doi.org/10.1016/j.tranon.2017.09.007 DO - 10.1016/j.tranon.2017.09.007 ID - Grzywa2017 ER - TY - JOUR AU - Chen, F. AU - Zhang, Y. AU - Varambally, S. AU - Creighton, C. J. PY - 2019 DA - 2019// TI - Molecular correlates of metastasis by systematic pan-cancer analysis across The Cancer Genome Atlas JO - Mol Cancer Res VL - 17 UR - https://doi.org/10.1158/1541-7786.MCR-18-0601 DO - 10.1158/1541-7786.MCR-18-0601 ID - Chen2019 ER - TY - JOUR AU - Godoy-Gijón, E. AU - Yuste-Chaves, M. AU - Santos-Briz, Á. PY - 2017 DA - 2017// TI - BRAF mutation status concordance between primary cutaneous melanomas and corresponding metastases: a review of the latest evidence JO - Actas Dermosifiliogr. VL - 108 UR - https://doi.org/10.1016/j.ad.2016.12.025 DO - 10.1016/j.ad.2016.12.025 ID - Godoy-Gijón2017 ER - TY - JOUR AU - Unamuno, B. u. s. t. o. s. B. AU - Murria Estal, R. AU - Pérez Simó, G. AU - Juan Jimenez, I. AU - Escutia Muñoz, B. AU - Rodríguez Serna, M. PY - 2017 DA - 2017// TI - Towards personalized medicine in melanoma: implementation of a clinical next-generation sequencing panel JO - Sci Rep. VL - 7 UR - https://doi.org/10.1038/s41598-017-00606-w DO - 10.1038/s41598-017-00606-w ID - Unamuno2017 ER - TY - JOUR AU - Reiman, A. AU - Kikuchi, H. AU - Scocchia, D. AU - Smith, P. AU - Tsang, Y. W. AU - Snead, D. PY - 2017 DA - 2017// TI - Validation of an NGS mutation detection panel for melanoma JO - BMC Cancer. VL - 17 UR - https://doi.org/10.1186/s12885-017-3149-0 DO - 10.1186/s12885-017-3149-0 ID - Reiman2017 ER - TY - JOUR AU - Siroy, A. E. AU - Boland, G. M. AU - Milton, D. R. AU - Roszik, J. AU - Frankian, S. AU - Malke, J. PY - 2015 DA - 2015// TI - Beyond BRAF(V600): clinical mutation panel testing by next-generation sequencing in advanced melanoma JO - J Investig Dermatol. VL - 135 UR - https://doi.org/10.1038/jid.2014.366 DO - 10.1038/jid.2014.366 ID - Siroy2015 ER - TY - JOUR AU - Casula, M. AU - Colombino, M. AU - Manca, A. AU - Caracò, C. AU - Botti, G. AU - Ascierto, P. A. PY - 2016 DA - 2016// TI - Low levels of genetic heterogeneity in matched lymph node metastases from patients with melanoma JO - J Investig Dermatol. VL - 136 UR - https://doi.org/10.1016/j.jid.2016.05.103 DO - 10.1016/j.jid.2016.05.103 ID - Casula2016 ER - TY - JOUR AU - Shain, A. H. AU - Joseph, N. M. AU - Yu, R. AU - Benhamida, J. AU - Liu, S. AU - Prow, T. PY - 2018 DA - 2018// TI - Genomic and transcriptomic analysis reveals incremental disruption of key signaling pathways during melanoma evolution JO - Cancer Cell VL - 34 UR - https://doi.org/10.1016/j.ccell.2018.06.005 DO - 10.1016/j.ccell.2018.06.005 ID - Shain2018 ER - TY - JOUR AU - Cirenajwis, H. AU - Ekedahl, H. AU - Lauss, M. AU - Harbst, K. AU - Carneiro, A. AU - Enoksson, J. PY - 2015 DA - 2015// TI - Molecular stratification of metastatic melanoma using gene expression profiling: prediction of survival outcome and benefit from molecular targeted therapy JO - Oncotarget. VL - 6 UR - https://doi.org/10.18632/oncotarget.3655 DO - 10.18632/oncotarget.3655 ID - Cirenajwis2015 ER - TY - JOUR AU - Miraflor, A. P. AU - Abreu, F. B. AU - Peterson, J. D. AU - Turner, S. A. AU - Amos, C. I. AU - Tsongalis, G. J. PY - 2017 DA - 2017// TI - Somatic mutation analysis in melanoma using targeted next generation sequencing JO - Exp Mol Pathol VL - 103 UR - https://doi.org/10.1016/j.yexmp.2017.08.006 DO - 10.1016/j.yexmp.2017.08.006 ID - Miraflor2017 ER - TY - STD TI - NCCN Clinical Practice Guidelines in Oncology. Cutaneous melanoma version 2.2019—March 12, 2019. https://www.nccn.org/professionals/physician_gls/default.aspx. Accessed 01 May 2019. UR - https://www.nccn.org/professionals/physician_gls/default.aspx ID - ref29 ER - TY - STD TI - Linee Guida AIOM 2018. Melanoma. https://www.aiom.it/linee-guida/linee-guida-aiom-2018-melanoma/. Accessed 01 May 2019. UR - https://www.aiom.it/linee-guida/linee-guida-aiom-2018-melanoma/ ID - ref30 ER - TY - JOUR AU - Hannan, E. J. AU - O’Leary, D. P. AU - MacNally, S. P. AU - Kay, E. W. AU - Farrell, M. A. AU - Morris, P. G. PY - 2017 DA - 2017// TI - The significance of BRAF V600E mutation status discordance between primary cutaneous melanoma and brain metastases: the implications for BRAF inhibitor therapy JO - Medicine VL - 96 UR - https://doi.org/10.1097/MD.0000000000008404 DO - 10.1097/MD.0000000000008404 ID - Hannan2017 ER - TY - JOUR AU - Casula, C. AU - Muggiano, A. AU - Cossu, A. AU - Budroni, M. AU - Caracò, C. AU - Ascierto, P. A. PY - 2009 DA - 2009// TI - Role of key-regulator genes in melanoma susceptibility and pathogenesis among patients from South Italy JO - BMC Cancer VL - 9 UR - https://doi.org/10.1186/1471-2407-9-352 DO - 10.1186/1471-2407-9-352 ID - Casula2009 ER - TY - JOUR AU - Palomba, G. AU - Colombino, M. AU - Contu, A. AU - Massidda, B. AU - Baldino, G. AU - Pazzola, A. PY - 2012 DA - 2012// TI - Prevalence of KRAS, BRAF, and PIK3CA somatic mutations in patients with colorectal carcinoma may vary in the same population: clues from Sardinia JO - J Transl Med VL - 10 UR - https://doi.org/10.1186/1479-5876-10-178 DO - 10.1186/1479-5876-10-178 ID - Palomba2012 ER -