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Table 2 Genes analyzed by qRT-PCR

From: Cryopreserved mesenchymal stem cells regain functional potency following a 24-h acclimation period

HMGB1

High mobility group box 1; DNA binding protein involved in tissue damage

TRL4

Toll-like receptor 4; play role in activation of innate immunity

TNF-α

Tumor necrosis factor alpha; upregulated in inflammation

CYCS

Cytochrome c; involved in initiation of apoptosis

BCL2

B-cell lymphoma 2; regulates apoptosis

BAX

BCL-2-like protein 4; apoptosis activator

CASP3

Caspase 3; apoptosis activator

NANOG

Transcription factor essential for pluripotency

SOX2

Sex determining region Y-box 2; transcription factor essential for pluripotency

OCT-4

Octamer-binding transcription factor 4; transcription factor essential for pluripotency

TNFAIP6

Tumor necrosis factor-inducible gene 6 protein; involved in macrophage polarization (M1 to M2 phenotype)

VEGF

Vascular endothelial growth factor; essential for angiogenesis

HMOX-1

Heme oxygenase 1; anti-inflammatory upregulates IL-10 and IL-1ra

STC-1

Stanniocalcin 1; regulation of metabolism and calcium/phosphate homeostasis

CAT

Catalase; catalyzes hydrogen peroxide to protect cell from reactive oxygen species

VCAM1

Vascular cell adhesion molecule 1; mediates adhesion of various immune cells

ICAM1

Intercellular adhesion molecule 1; mediates adhesion of leukocytes when activated