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Table 4 Clinical and demographic characteristics in cirrhotic patients subgroup with and without HCC occurrence (N = 731)—univariate analysis

From: Incidence and risk factors of early HCC occurrence in HCV patients treated with direct acting antivirals: a prospective multicentre study

Variables Cirrhotic patients without HCC (n = 696) Cirrhotic patients with HCC (n = 35) p
Male gender, n (%) 367 (52.7) 24 (70.6) 0.04
Age, years, ≥ 67, n (%) 373 (53.6) 23 (67.6) 0.11
BMI, kg/m2 ≥ 26, n (%) 285 (51.4) 14 (42.4) 0.32
Presence of diabetes, n (%) 89 (12.8) 10 (29.4) 0.006
CTP B class, n (%) 72 (10.3) 10 (29.4) 0.001
HCV genotype 1, n (%) 524 (76.2) 28 (82.4) 0.41
24 weeks treatment duration, n (%) 311 (44.6) 19 (55.9) 0.19
Baseline HCV-RNA, UI/ml, ≥ 1 × 106, n (%) 381 (54.7) 13 (38.2) 0.06
Liver stiffness, kPa ≥ 20, n (%) 176 (49.7) 24 (72.7) 0.01
SVR12, n (%) 682 (97.8) 32 (94.1) 0.16
DAA-SOF based, n (%) 555 (79.6) 30 (88.2) 0.31
DAA-RBV included, n (%) 535 (76.8) 15 (44.1) < 0.0001
DAA-SOF + RBV, n (%) 438 (63.0) 12 (35.3) 0.001
DAA-SOF without RBV, n (%) 113 (16.2) 18 (52.9) < 0.0001
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