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Table 4 Clinical and demographic characteristics in cirrhotic patients subgroup with and without HCC occurrence (N = 731)—univariate analysis

From: Incidence and risk factors of early HCC occurrence in HCV patients treated with direct acting antivirals: a prospective multicentre study

Variables

Cirrhotic patients without HCC (n = 696)

Cirrhotic patients with HCC (n = 35)

p

Male gender, n (%)

367 (52.7)

24 (70.6)

0.04

Age, years, ≥ 67, n (%)

373 (53.6)

23 (67.6)

0.11

BMI, kg/m2 ≥ 26, n (%)

285 (51.4)

14 (42.4)

0.32

Presence of diabetes, n (%)

89 (12.8)

10 (29.4)

0.006

CTP B class, n (%)

72 (10.3)

10 (29.4)

0.001

HCV genotype 1, n (%)

524 (76.2)

28 (82.4)

0.41

24 weeks treatment duration, n (%)

311 (44.6)

19 (55.9)

0.19

Baseline HCV-RNA, UI/ml, ≥ 1 × 106, n (%)

381 (54.7)

13 (38.2)

0.06

Liver stiffness, kPa ≥ 20, n (%)

176 (49.7)

24 (72.7)

0.01

SVR12, n (%)

682 (97.8)

32 (94.1)

0.16

DAA-SOF based, n (%)

555 (79.6)

30 (88.2)

0.31

DAA-RBV included, n (%)

535 (76.8)

15 (44.1)

< 0.0001

DAA-SOF + RBV, n (%)

438 (63.0)

12 (35.3)

0.001

DAA-SOF without RBV, n (%)

113 (16.2)

18 (52.9)

< 0.0001