Table 6 Pathways enriched in the low-risk group according to gene set enrichment analysis (GSEA)
Name | Size | ES | NES | NOM P | FDR q | FWER P | Rank at max | Leading edge |
|---|---|---|---|---|---|---|---|---|
KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS | 132 | − 0.727497 | − 3.170449 | 0 | 0 | 0 | 9024 | Tags = 67%, list = 16%, signal = 79% |
KEGG_OXIDATIVE_PHOSPHORYLATION | 118 | − 0.708458 | − 3.066339 | 0 | 0 | 0 | 10,688 | Tags = 70%, list = 19%, signal = 87% |
KEGG_PEROXISOME | 78 | − 0.755321 | − 3.048664 | 0 | 0 | 0 | 9185 | Tags = 72%, list = 17%, signal = 86% |
KEGG_ENDOCYTOSIS | 176 | − 0.666864 | − 3.027353 | 0 | 0 | 0 | 8682 | Tags = 59%, list = 16%, signal = 70% |
KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION | 44 | − 0.818906 | − 2.976677 | 0 | 0 | 0 | 5843 | Tags = 80%, list = 11%, signal = 89% |
KEGG_FOCAL_ADHESION | 197 | − 0.636304 | − 2.969007 | 0 | 0 | 0 | 9112 | Tags = 54%, list = 16%, signal = 65% |
KEGG_PARKINSONS_DISEASE | 114 | − 0.687936 | − 2.94244 | 0 | 0 | 0 | 8989 | Tags = 61%, list = 16%, signal = 73% |
KEGG_NEUROTROPHIN_SIGNALING_PATHWAY | 125 | − 0.679093 | − 2.935972 | 0 | 0 | 0 | 9509 | Tags = 62%, list = 17%, signal = 74% |
KEGG_ALZHEIMERS_DISEASE | 158 | − 0.646806 | − 2.935276 | 0 | 0 | 0 | 8989 | Tags = 56%, list = 16%, signal = 67% |
KEGG_HUNTINGTONS_DISEASE | 174 | − 0.64174 | − 2.909377 | 0 | 0 | 0 | 8989 | Tags = 56%, list = 16%, signal = 66% |
KEGG_PROSTATE_CANCER | 89 | − 0.716898 | − 2.907305 | 0 | 0 | 0 | 9112 | Tags = 63%, list = 16%, signal = 75% |
KEGG_LYSOSOME | 119 | − 0.674316 | − 2.895725 | 0 | 0 | 0 | 9385 | Tags = 64%, list = 17%, signal = 77% |
KEGG_PATHWAYS_IN_CANCER | 321 | − 0.597361 | − 2.89323 | 0 | 0 | 0 | 10,390 | Tags = 53%, list = 19%, signal = 65% |
KEGG_TIGHT_JUNCTION | 128 | − 0.653417 | − 2.876733 | 0 | 0 | 0 | 9304 | Tags = 61%, list = 17%, signal = 73% |
KEGG_WNT_SIGNALING_PATHWAY | 149 | − 0.64552 | − 2.851381 | 0 | 0 | 0 | 10,037 | Tags = 56%, list = 18%, signal = 69% |
KEGG_ADHERENS_JUNCTION | 68 | − 0.726372 | − 2.841678 | 0 | 0 | 0 | 7905 | Tags = 71%, list = 14%, signal = 82% |
KEGG_ENDOMETRIAL_CANCER | 52 | − 0.750658 | − 2.820001 | 0 | 0 | 0 | 9383 | Tags = 75%, list = 17%, signal = 90% |
KEGG_CHRONIC_MYELOID_LEUKEMIA | 73 | − 0.694979 | − 2.816546 | 0 | 0 | 0 | 9112 | Tags = 62%, list = 16%, signal = 74% |
KEGG_REGULATION_OF_ACTIN_CYTOSKELETON | 211 | − 0.606974 | − 2.81045 | 0 | 0 | 0 | 9156 | Tags = 53%, list = 17%, signal = 63% |
KEGG_CITRATE_CYCLE_TCA_CYCLE | 30 | − 0.842038 | − 2.791856 | 0 | 0 | 0 | 5709 | Tags = 83%, list = 10%, signal = 93% |
KEGG_INSULIN_SIGNALING_PATHWAY | 137 | − 0.639309 | − 2.781884 | 0 | 0 | 0 | 9112 | Tags = 56%, list = 16%, signal = 67% |
KEGG_ERBB_SIGNALING_PATHWAY | 86 | − 0.681992 | − 2.769589 | 0 | 0 | 0 | 9112 | Tags = 62%, list = 16%, signal = 74% |