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Table 6 Multivariate analysis of factors influencing survival of patients with PTC

From: Expression of proteins related to autotaxin–lysophosphatidate signaling in thyroid tumors

Included parameters Disease-free survival Overall survival
Hazard ratio 95% CI p-value Hazard ratio 95% CI p-value
Age (years) 0.617    0.007
 < 45 versus ≥ 45 1.282 0.485–3.389   16.39 2.129–126.2  
Sex 0.508    0.925
 Male versus female 0.700 0.244–2.011   1.065 0.290–3.915  
Tumor size (cm) 0.816    0.188
 ≤ 2.0 versus > 2.0 1.134 1.134–3.268   2.005 0.711–5.653  
Tumor extension 0.378    0.440
 Intrathyroidal versus extrathyroidal 0.641 0.239–1.722   0.647 0.214–1.955  
LN metastasis 0.019    0.064
 No versus yes 5.978 1.339–26.69   2.940 0.939–9.202  
ATX 0.997    0.360
 Negative versus positive 0.998 0.334–2.981   1.633 0.571–4.665  
LPA1 0.688    0.252
 Negative versus positive 0.805 0.278–2.327   2.093 0.592–7.403  
  1. Italic values represent significance of p-value (p < 0.05)