Expression of proteins related to autotaxin–lysophosphatidate signaling in thyroid tumors

Table 6 Multivariate analysis of factors influencing survival of patients with PTC

Included parameters	Disease-free survival			Overall survival
Included parameters	Hazard ratio	95% CI	p-value	Hazard ratio	95% CI	p-value
Age (years)			0.617			0.007
< 45 versus ≥ 45	1.282	0.485–3.389		16.39	2.129–126.2
Sex			0.508			0.925
Male versus female	0.700	0.244–2.011		1.065	0.290–3.915
Tumor size (cm)			0.816			0.188
≤ 2.0 versus > 2.0	1.134	1.134–3.268		2.005	0.711–5.653
Tumor extension			0.378			0.440
Intrathyroidal versus extrathyroidal	0.641	0.239–1.722		0.647	0.214–1.955
LN metastasis			0.019			0.064
No versus yes	5.978	1.339–26.69		2.940	0.939–9.202
ATX			0.997			0.360
Negative versus positive	0.998	0.334–2.981		1.633	0.571–4.665
LPA1			0.688			0.252
Negative versus positive	0.805	0.278–2.327		2.093	0.592–7.403

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